DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and Lpar3

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_075359.1	Gene:	Lpar3 / 65086	MGIID:	1929469	Length:	354	Species:	Mus musculus

Alignment Length:	322	Identity:	74/322 - (22%)
Similarity:	138/322 - (42%)	Gaps:	62/322 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VAIVSIIG----------NVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGL 105
            :.||..:|          |.|||......||......|.:.:||.||...| :...|.:..:..:
Mouse    30 LVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAG-IAYVFLMFNTGPV 93

  Fly   106 PRNLHACLFTVS-------LLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMC 163
            .:.|     ||:       ||....|.|:..|:.::|:|:.:|:....:|...:.|..:.|: :.
Mouse    94 SKTL-----TVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLIL-LV 152

  Fly   164 WVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQ 228
            |.....:|.:|..||:...|.:.......:...:||:|...:.::. ..:|:|.|..|| :.:|:
Mouse   153 WAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLA-FFIMVAVYVRIY-MYVKR 215

  Fly   229 VRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICW 293
            ...:::.:.:..:|||.:...:.          .|::.||||                  |::||
Mouse   216 KTNVLSPHTSGSISRRRAPMKLM----------KTVMTVLGA------------------FVVCW 252

  Fly   294 IPLYTINCIKAF-CPDCYV-HPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMM 353
            .|...:..:... |..|.| |.|  .:.::|:.|||.:||::|:|..:|    :.|.:.||:
Mouse   253 TPGLVVLLLDGLNCKQCNVQHVK--RWFLLLALLNSVMNPIIYSYKDED----MYNTMRKMI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	42/184 (23%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	66/294 (22%)
Lpar3	NP_075359.1	7tm_4	42..309	CDD:304433	71/310 (23%)
		7tm_1	48..293	CDD:278431	65/283 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910