DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdoR and BDKRB2

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_000614.1 Gene:BDKRB2 / 624 HGNCID:1030 Length:391 Species:Homo sapiens


Alignment Length:365 Identity:88/365 - (24%)
Similarity:147/365 - (40%) Gaps:76/365 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 TDFSFEGPLL--PLHAATTSKDAKDSDSPSSE----LNIPYTVFEVLVAIVSIIGNVLVIIVFRR 68
            |..||...:|  .|...|.:.....|..|..|    ||.....|..::.:::.:.|:.|:.||..
Human    20 TTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCL 84

  Fly    69 ERKLRRRTNYYIVSLAMADLLVGALGIPF-AILASMGLPRNLHACLFTVSLLVVLCTI------- 125
            .:........|:.:||.|||:: |.|:|| ||..|     |....||..:|..|:..|       
Human    85 HKSSCTVAEIYLGNLAAADLIL-ACGLPFWAITIS-----NNFDWLFGETLCRVVNAIISMNLYS 143

  Fly   126 SIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGW-----HADVNHN 185
            ||..|:.||:|||.|::..|:..|....|.|.....:.| ..|::...|:..:     ::|..||
Human   144 SICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIW-GCTLLLSSPMLVFRTMKEYSDEGHN 207

  Fly   186 -QECLFVEVMDYNYLVFLYFATI---ITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSS 246
             ..|    |:.|..|::..|..:   :...||.|:..|    ....|:.|::..|......    
Human   208 VTAC----VISYPSLIWEVFTNMLLNVVGFLLPLSVIT----FCTMQIMQVLRNNEMQKFK---- 260

  Fly   247 AAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIP---------LYTINCI 302
                ::.|..|                    ||..:.:::|.|:|||:|         |:.:..:
Human   261 ----EIQTERR--------------------ATVLVLVVLLLFIICWLPFQISTFLDTLHRLGIL 301

  Fly   303 KAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFR 342
            .: |.|..:...:|.....:::.||.:||::|....|.||
Human   302 SS-CQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFR 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 50/184 (27%)
7tm_1 58..334 CDD:278431 72/301 (24%)
BDKRB2NP_000614.1 7tmA_BK-2 58..343 CDD:320503 77/327 (24%)
TM helix 1 60..84 CDD:320503 5/23 (22%)
TM helix 2 93..114 CDD:320503 10/21 (48%)
TM helix 3 131..153 CDD:320503 6/21 (29%)
TM helix 4 176..192 CDD:320503 2/16 (13%)
TM helix 5 222..245 CDD:320503 5/26 (19%)
TM helix 6 269..291 CDD:320503 7/21 (33%)
TM helix 7 311..336 CDD:320503 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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