DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and PTGDR

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_000944.1 Gene:PTGDR / 5729 HGNCID:9591 Length:359 Species:Homo sapiens


Alignment Length:276 Identity:51/276 - (18%)
Similarity:104/276 - (37%) Gaps:60/276 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 IIGNVLVIIVFRR-------ERKLRRRTNYY---IVSLAMADLLVGALGIPFAILASMGLPRNL- 109
            ::||:|.:.:..|       .|.||...:.:   :..|.:.|||...|..| .:||:....|:| 
Human    31 LLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSP-VVLAAYAQNRSLR 94

  Fly   110 -----------HACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTR--------T 155
                       .|..|.:|...:..|:.   |:|::::.:.::.:|..|.|::..|        .
Human    95 VLAPALDNSLCQAFAFFMSFFGLSSTLQ---LLAMALECWLSLGHPFFYRRHITLRLGALVAPVV 156

  Fly   156 AIFIISMCWVAGTIVGFLPLFGWHADVNH--NQECLFVEVMDYNYLVFLYFATIITPALLMLAFY 218
            :.|.::.|        .||..|:...|.:  ...|....|.:...|..|.::.:.:..:.:|...
Human   157 SAFSLAFC--------ALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLA 213

  Fly   219 THIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLS 283
            |.:..  :..:|.:..|:  ..|.|...:.......|...|.         .|..:.::...:|.
Human   214 TVLCN--LGAMRNLYAMH--RRLQRHPRSCTRDCAEPRADGR---------EASPQPLEELDHLL 265

  Fly   284 IIVL---FFMICWIPL 296
            ::.|   .|.:|.:|:
Human   266 LLALMTVLFTMCSLPV 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 38/195 (19%)
7tm_1 58..334 CDD:278431 51/274 (19%)
PTGDRNP_000944.1 7tmA_PGD2 17..335 CDD:320268 51/276 (18%)
TM helix 1 18..44 CDD:320268 3/12 (25%)
TM helix 2 61..87 CDD:320268 8/26 (31%)
TM helix 3 105..135 CDD:320268 6/32 (19%)
TM helix 4 147..169 CDD:320268 5/29 (17%)
TM helix 5 195..224 CDD:320268 3/30 (10%)
TM helix 6 258..288 CDD:320268 5/24 (21%)
TM helix 7 302..327 CDD:320268
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.