DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and rxfp2b

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001315011.1	Gene:	rxfp2b / 566888	ZFINID:	ZDB-GENE-110408-27	Length:	750	Species:	Danio rerio

Alignment Length:	362	Identity:	83/362 - (22%)
Similarity:	150/362 - (41%)	Gaps:	83/362 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 HAATTSKDAKDSDSPSS--EL--NIPYTVFEVLVAIVSIIGNVLVI---IVFRRERKLRRRTNYY 79
            :|....|...:||..||  :|  |:...|...::|.::..||:.||   .|.|.|..|..   :.
Zfish   387 YAPHVRKCKPNSDGLSSFEDLLANVVLRVSVWVMAFITCFGNLFVIGMRTVLRAENNLHA---FC 448

  Fly    80 IVSLAMADLLVGA----LGIPFAILASMGLPRNLHACL-----FTVSLLVVLCT-ISIFCLVAVS 134
            |..|..||.|:|.    :|| |.:.......:|....:     .|:..|.:|.: :|:..|..::
Zfish   449 IKVLCCADCLMGVYLFFVGI-FDVKFRGEYNKNAKVWMESLECRTIGFLAMLSSEVSVMLLTYLT 512

  Fly   135 VDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPL-----FGWHADVN------HNQEC 188
            ::::..|::|.::.|..:.:|...::|: |:.|..:..:||     ||.:..:|      |::..
Zfish   513 LEKFLVIVFPFSHLRPSKCQTFTVLVSI-WLLGISIAAVPLLNEDTFGNYYGLNGVCFPLHSERL 576

  Fly   189 LFVEVMDYNYLVFLYFATIITPALLMLAF------YTHIYRVIIKQVRQIVTMNPASDLSRRSSA 247
            .......|:..:||        .|.:|||      |:.::..|.|      |...|::|
Zfish   577 EKPVAKGYSTGIFL--------GLNLLAFLIIVVSYSSMFYSIYK------TGIRATEL------ 621

  Fly   248 AVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVH 312
                   |||              ..|||........||....:||||::.:..:...  :..:.
Zfish   622 -------PGR--------------LHRDVAMAHRFFFIVFSDALCWIPIFMVKILSLL--EVEIP 663

  Fly   313 PKLTLFCII-LSHLNSAVNPVLYAYHLKDFRAALKNL 348
            ..:|.:.:| :..:|||:||:||......||..:::|
Zfish   664 GTITSWVVIFILPINSALNPILYTLTTSFFREQVEHL 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	45/197 (23%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	68/306 (22%)
rxfp2b	NP_001315011.1	LDLa	39..74	CDD:238060
		leucine-rich repeat	114..132	CDD:275380
		LRR_RI	130..360	CDD:238064
		leucine-rich repeat	133..156	CDD:275380
		LRR_8	156..215	CDD:290566
		leucine-rich repeat	157..180	CDD:275380
		leucine-rich repeat	181..204	CDD:275380
		LRR_8	203..288	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..253	CDD:275380
		leucine-rich repeat	254..277	CDD:275380
		LRR_8	277..336	CDD:290566
		leucine-rich repeat	278..301	CDD:275380
		leucine-rich repeat	302..325	CDD:275380
		LRR_8	324..378	CDD:290566
		leucine-rich repeat	326..349	CDD:275380
		leucine-rich repeat	350..369	CDD:275380
		7tm_4	419..>556	CDD:304433	33/141 (23%)
		7tm_1	<487..686	CDD:278431	50/242 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910