Protein Alignment AdoR and adora2aa

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001034904.1
• Gene: adora2aa / 561701
• ZFINID: ZDB-GENE-080723-28
• Length: 442
• Species: Danio rerio
• Alignment Length: 377
• Identity: 130/377 - (34%)
• Similarity: 200/377 - (53%)
• Gaps: 55/377 - (14%)

  Fly    41 NIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGL 105
            ::.|.:.|:|:|::|::|||||.........|:..||:::||||:||:.||.|.|||:|:.|.|.
Zfish     7 DVLYMILELLIALLSVLGNVLVCWAVGLNSNLQSITNFFVVSLAVADIAVGVLAIPFSIVISTGF 71

  Fly   106 PRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIV 170
            ..|.:.|||....::||...|||.|:|:::|||.||..|:.|:..|..:.|..||::|||...|:
Zfish    72 CANFYGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIKIPLRYNSLVTGQRARGIIAICWVLSVII 136

  Fly   171 GFLPLFGWH---ADVNHN-------QECLFVEVMDYNYLV-FLYFATIITPALLMLAFYTHIYRV 224
            |..|:.|||   ....||       .||||.||:..:|:| |.:||.::.|.|||||.|..|:..
Zfish   137 GLTPMLGWHKARLQEGHNGTCPPGMMECLFEEVVVMDYMVYFNFFACVLVPLLLMLAIYLRIFMA 201

  Fly   225 IIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFF 289
            ...|::.|.:.....:|..||:.                         :::|.|.::|:|||..|
Zfish   202 ARHQLKCIESKAIPCELKSRSTL-------------------------QKEVHAAKSLAIIVGLF 241

  Fly   290 MICWIPLYTINCIKAFCPDCYVHPKLTLF-CIILSHLNSAVNPVLYAYHLKDFRAALKNLL-LKM 352
            .:||:||:.|||...|||:|...|.|.:: .|||||.||.|||.:|||.:::||...:.:: ..:
Zfish   242 AVCWLPLHIINCFTLFCPECERPPALIMYLAIILSHANSVVNPFIYAYRIREFRHTFRKIVRYHI 306

  Fly   353 MG----VDIDQQAEAIHRFSVASQHRLQ-------------SMDSNMRSTQP 387
            :|    :..:.......|.|||...|::             |..|:..|.:|
Zfish   307 LGRREPLSCNGSTRTSTRTSVADSLRIKVNGLVRELYAEQSSTTSSCESAEP 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	76/178 (43%)
		7tm_1	58..334	CDD:278431	110/287 (38%)
adora2aa	NP_001034904.1	7tm_4	16..>136	CDD:304433	51/119 (43%)
		7tm_1	24..287	CDD:278431	110/287 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585511
Domainoid	1	1.000	203	1.000	Domainoid score	I2915
eggNOG	1	0.900	-	-		E33208_3BF5B
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	1	1.000	-	-		otm25428
orthoMCL	1	0.900	-	-		OOG6_107098
Panther	1	1.100	-	-	LDO	PTHR24246
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5322
SonicParanoid	1	1.000	-	-		X919
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.730