DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and htr1b

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001122181.1	Gene:	htr1b / 561647	ZFINID:	ZDB-GENE-081022-141	Length:	380	Species:	Danio rerio

Alignment Length:	385	Identity:	104/385 - (27%)
Similarity:	171/385 - (44%)	Gaps:	58/385 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YFSITDFSFEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEV--LVAIVSIIGNVLVIIVFRR 68
            ||..|...||  :|.....|.......:|..........|:..|  |:.:.:|:.|..||....:
Zfish     6 YFKPTPAHFE--VLNSSTGTNVTLTPKTDEKQESFAFQVTLSSVLGLITLATILSNAFVIATISQ 68

  Fly    69 ERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLH--ACLFTVSLLVVLCTISIFCLV 131
            .|||:...|:.|.|||:.||||..|.:|..:|.::.....|.  .|...:|..:..||.||..|.
Zfish    69 SRKLQTPANFLIASLAVTDLLVSVLVMPICVLYTVTREWTLGQVICDIWLSSDITCCTASILHLC 133

  Fly   132 AVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWH-------ADVNHNQECL 189
            .:::||||||...:.|::......|..:::..|:....:. ||.|.|.       ...:.|.:.:
Zfish   134 VIALDRYWAITDAVEYAKKRTQARAAGMVATAWIIAISIS-LPPFFWRQVKAGELTTCSVNTDHI 197

  Fly   190 FVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNP--------ASDLSRRSS 246
            |       |.::..|.....|.||::|.|..||   ::..::|:..:|        ::.||..|.
Zfish   198 F-------YTIYSTFGAFYIPTLLLIALYGRIY---VEARKRILKQSPKKPGKRLTSAHLSTNSP 252

  Fly   247 AAVVQVTTP---GR------GGHTGT--MLRV-----------LGAARKRDVKATQNLSIIVLFF 289
            |:|.. |:|   ||      .|..|:  .:||           :.|||:|  |||:.|.||:..:
Zfish   253 ASVAS-TSPLHCGRQDLCSDSGSLGSDNQIRVTVSDSLLEKKRISAARER--KATKTLGIILGAY 314

  Fly   290 MICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLL 349
            ::||:|.:....:...|..|: .|:|..|...|.::||.:||::|.....||:.|...::
Zfish   315 IVCWLPFFIYTLLIPLCSSCF-SPELFDFFTWLGYVNSLINPIIYTMSNDDFKKAFHKVI 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	49/176 (28%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	88/314 (28%)
htr1b	NP_001122181.1	7tm_1	59..358	CDD:278431	88/313 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910