Protein Alignment AdoR and adora2b

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001034902.1
• Gene: adora2b / 560100
• ZFINID: ZDB-GENE-060511-1
• Length: 351
• Species: Danio rerio
• Alignment Length: 359
• Identity: 121/359 - (33%)
• Similarity: 186/359 - (51%)
• Gaps: 58/359 - (16%)

  Fly    44 YTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRN 108
            |...|:::|::||.|||||.........|:..|||::||||:||:|||.|.|||||..|:||..:
Zfish     5 YIAIELVIAVLSIAGNVLVCWAVAINSTLKNATNYFLVSLAVADILVGCLAIPFAITISIGLWSD 69

  Fly   109 LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFL 173
            .:.|||....::||...|||.|:||::|||.|:..|:.|...|..:.|..||::.|:...|:|.:
Zfish    70 FYGCLFLACFVLVLTQSSIFSLLAVAIDRYLAVKIPLRYRELVTGKRAREIITILWILSFIIGLI 134

  Fly   174 PLFGWHA---------------------DVNHNQ---------ECLFVEVMDYNYLV-FLYFATI 207
            |..||:.                     |....:         ||.|.:|:|.:|:| |.:|..:
Zfish   135 PFVGWNRKDLACSRNKSGSLQTSNSSDDDAAETETGFLQSCYLECFFEKVVDMSYMVYFNFFGCV 199

  Fly   208 ITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAAR 272
            :.|.|:||..|..|:.|..||:|||......|:               |...|.|.:
Zfish   200 LPPLLIMLGIYAKIFTVARKQLRQIELKCSVSN---------------GENQHHGLL-------- 241

  Fly   273 KRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYH 337
            :|:::|.::|||||..|.:||:|::.:||:..|..:......:....|||||.||||||::|||.
Zfish   242 QREIRAAKSLSIIVGLFALCWLPVHILNCLTLFYSELKKPSFIMNIAIILSHANSAVNPIIYAYR 306

  Fly   338 LKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVAS 371
            :::||...:    |::...|..|.:.::|.|..|
Zfish   307 IREFRVTFR----KILNRHILCQRDELYRSSNGS 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	72/198 (36%)
		7tm_1	58..334	CDD:278431	105/306 (34%)
adora2b	NP_001034902.1	7tm_4	12..>131	CDD:304433	52/118 (44%)
		7tm_1	19..303	CDD:278431	105/306 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585516
Domainoid	1	1.000	203	1.000	Domainoid score	I2915
eggNOG	1	0.900	-	-		E33208_3BF5B
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	1	1.000	-	-		otm25428
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24246
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5322
SonicParanoid	1	1.000	-	-		X919
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.870