Protein Alignment AdoR and Chrm5

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_059058.1
• Gene: Chrm5 / 53949
• RGDID: 620027
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 491
• Identity: 102/491 - (20%)
• Similarity: 161/491 - (32%)
• Gaps: 192/491 - (39%)

  Fly    42 IPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFA-------- 98
            |...|...:|::::|:|||||:|.|:...:|:...|||::|||.|||::|...:...
  Rat    30 ITIAVVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGR 94

  Fly    99 -ILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISM 162
             :|.|:       ||...::|..|....|:..|:.:|.|||::|..|:.|......:.|..:|.:
  Rat    95 WVLGSL-------ACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGL 152

  Fly   163 CWVAGTIVGFLPLFGWHADVNHN----QECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYR 223
            .|:...|:....:..|...|...    .||....:.:.........|....|..:|...|..|||
  Rat   153 AWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYR 217

  Fly   224 VIIKQVRQIVTM------------------------------------NPAS-DLSRRSSAA--- 248
            ...|:.:.:..:                                    |.|| ..||||::.
  Rat   218 ETEKRTKDLADLQGSDSVAEAKKREPAQRTLLRSFFSCPRPSLAQRERNQASWSSSRRSTSTTGK 282

  Fly   249 -------------VVQVTT------------------------------PGRGGHT--------- 261
                         ..||||                              ||:..:|
  Rat   283 TTQATDLSADWEKAEQVTTCSSYPSSEDEAKPTTDPVFQMVYKSEAKESPGKESNTQETKETVVN 347

  Fly   262 ----------------------------------------GTM--------LRVLGAA------- 271
                                                    ||.        ::::..:
  Rat   348 TRTENSDYDTPKYFLSPAAAHRLKSQKCVAYKFRLVVKADGTQETNNGCRKVKIMPCSFPVSKDP 412

  Fly   272 ---------------RKRDV-----KATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLT 316
                           |||.|     ||.|.||.|:|.|:|.|.|...:..:..||..|.   .:|
  Rat   413 STKGPDPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCV---PVT 474

  Fly   317 LFCI--ILSHLNSAVNPVLYAYHLKDFRAALKNLLL 350
            |:.:  .|.::||.:||:.||...:.||...|.|||
  Rat   475 LWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	46/180 (26%)
		7tm_1	58..334	CDD:278431	90/457 (20%)
Chrm5	NP_059058.1	7tm_4	39..>166	CDD:304433	39/133 (29%)
		7tm_1	46..255	CDD:278431	49/215 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..295		7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..346		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910