Protein Alignment AdoR and MC3R

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_063941.3
• Gene: MC3R / 4159
• HGNCID: 6931
• Length: 323
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 84/364 - (23%)
• Similarity: 151/364 - (41%)
• Gaps: 76/364 - (20%)

  Fly    17 PLLP-----LHAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRT 76
            |.||     |.|...|.  :.|.:...::.|...|| :.:.|||::.|:|||:...|...|....
Human    12 PTLPNGSEHLQAPFFSN--QSSSAFCEQVFIKPEVF-LSLGIVSLLENILVILAVVRNGNLHSPM 73

  Fly    77 NYYIVSLAMADLLVGALG----IPFAILASMGLP---------RNLHACLFTVSLLVVLCTISIF 128
            .:::.|||:||:||....    |..||:.|..|.         .|:...:..:||:..:|.
Human    74 YFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICN---- 134

  Fly   129 CLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEV 193
             |:|::||||..|.|.:.|...:..|.|:.:|...||...:.|.:.:      |....:.:.|
Human   135 -LLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI------VYSESKMVIV-- 190

  Fly   194 MDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRG 258
                .|:.::||.:    |||...|.|::......|::|..:.||..::.:..:.
Human   191 ----CLITMFFAMM----LLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSC---------- 237

  Fly   259 GHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPD-----CYVHPKLTLF 318
                             :|....::|::..|:.||.|.:....:...||.     ||.....|..
Human   238 -----------------MKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYL 285

  Fly   319 CIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDI 357
            .:|:  .||.::|::||:...:.|...:.:|....|:::
Human   286 VLIM--CNSVIDPLIYAFRSLELRNTFREILCGCNGMNL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	49/180 (27%)
		7tm_1	58..334	CDD:278431	66/293 (23%)
MC3R	NP_063941.3	7tm_4	45..>170	CDD:304433	38/130 (29%)
		7tm_1	55..299	CDD:278431	66/293 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910