Protein Alignment AdoR and mAChR-B

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Alignment Length: 911
• Identity: 180/911 - (19%)
• Similarity: 317/911 - (34%)
• Gaps: 305/911 - (33%)

  Fly     8 SITDFSFEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFE-VLVA-------IVSIIGNVLVII 64
            |.:|....||:||                      |:.::: :|:|       |:::.||:||::
  Fly   114 SSSDSEILGPVLP----------------------PFALWQTILIAICLAICIILTVGGNILVLL 156

  Fly    65 VFRRERKLRRRTNYYIVSLAMADLLVGALGIPF-AILASMGL----PRNLHACLFTVSLLVVLCT 124
            .|..:|.:|:.:||:|.|||..|:|:|.:.:|| .|....|.    |.   .|...:|:...:|.
  Fly   157 AFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPM---LCDLWLSVDYTVCL 218

  Fly   125 ISIFCLVAVSVDRYWAILYPMAYSRNVRTRT-AIFIISMCWVAGTIVGFLPLFGWHADVNHNQ-- 186
            :|.:.::.:::|||.::.....| |:.|||| .|:::::.|:...::.|:.:|||........
  Fly   219 VSQYTVLLITIDRYCSVKIAAKY-RSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLL 282

  Fly   187 --ECL--FVEVMDYN--YLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRS 245
              :|.  |::...:|  .::..|:.|:|    ::...|..||:.             |.|:.:||
  Fly   283 PGQCAVQFLKDPIFNTALIIGYYWTTLI----VLFVLYAGIYKT-------------AYDMQKRS 330

  Fly   246 SA---------AVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINC 301
            .|         |:......|..||...    :|...::.:|....|:
  Fly   331 EAKQRKMQSMVALSAGAMSGMAGHAAG----IGVIEEKILKTKVELA------------------ 373

  Fly   302 IKAFCPDCYVHPKLTLFC-IILSHLNSA--VNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEA 363
                 .|   ...|...| .::..|:.:  .||:..|..                  ::::....
  Fly   374 -----GD---QTDLDSACTTVIKRLSGSGQANPLAVATE------------------EVEKMTPE 412

  Fly   364 IHRFSVA-----SQHRLQSMDS--NMRSTQPRLYVGEYSPIWLRQQ---QEALKNSQLLPKCGVV 418
            ..|.|.|     ::.|..::|:  :.||:.|.....|.|.:...||   |:.|.|.:.....|:|
  Fly   413 QRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRSSIGLV 477

  Fly   419 SPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEF---------PSPAPGSQ---- 470
               |.      |..|.:.|   |...|:.::::.::..|..:::         .||...:|
  Fly   478 ---FG------AQAALLAT---RGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRAQSKEE 530

  Fly   471 -RSSERNSSSTVP--------PAPPAPAKPSVPSASYDNHNYSFSQDEDEDDDDLEFEDVFVPAS 526
             ||...:.:...|        |.||.. :|...|.|      :.||..:.|    ...|:..|.:
  Fly   531 MRSLHHHQNQQQPHHQHHQNQPNPPLD-RPKRTSCS------TLSQIAEHD----RLVDLSAPPT 584

  Fly   527 --SVPNPVQP-GIDPVELRRSLALVMREKLR--------------------SDDTDSRPMGN--- 565
              :..:|:.| .:.|:|       |..:::.                    |||...||.||
  Fly   585 LLNTSDPLSPVDLAPIE-------VPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSG 642

  Fly   566 NQDLPIDEQSRERPLSTQTSPTNGPLPALLRAKLLAGNSNSAHCLPGSTASPAPQEQSGIFVIDS 630
            |.:|.:          |....||..|..:..:..:.     |.....||.||....|....|:
  Fly   643 NSELAL----------TYDLMTNSELRYMDESSAML-----ASVTANSTTSPNDSVQGKPPVL-- 690

  Fly   631 EASPGSNGHKPKYRKGTAFTRSSLKKSRSCNCSSIAKGRGVHDEPSSNLCRDQESS--VLPQHPQ 693
            ...|.:..:.||         |:|.:|.|             ..||.|....|..|  :.|.|.|
  Fly   691 PPPPPARRNPPK---------SNLNQSLS-------------QTPSQNQSPSQSLSLNLNPNHNQ 733

  Fly   694 PANHPTENFFS----------------------------------------PLRSVGSFMQHSN- 717
            ..:...|...:                                        |.|...|.|:.|:
  Fly   734 SQSQSIEEAVAIEKRLLVSYTGIEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSPMETSSK 798

  Fly   718 ---LFHFLQPHAARPTSSTASSTASTP------TPSPPPMGQAQEESVPVGLTTSSPSLLATSAE 773
               |:..:.|....|...|::....||      || |.|:.:.:|.......|...||...|::.
  Fly   799 DAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTP-PVPLERIEERETSDSNTNKMPSTSGTTSS 862

  Fly   774 S 774
            :
  Fly   863 T 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	49/188 (26%)
		7tm_1	58..334	CDD:278431	67/301 (22%)
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	54/211 (26%)
		7tm_4	150..>336	CDD:304433	54/206 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910