Protein Alignment AdoR and mAChR-A

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_523844.2
• Gene: mAChR-A / 37892
• FlyBaseID: FBgn0000037
• Length: 805
• Species: Drosophila melanogaster
• Alignment Length: 754
• Identity: 136/754 - (18%)
• Similarity: 247/754 - (32%)
• Gaps: 257/754 - (34%)

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIP-FAILASMGL-PRNLHAC 112
            :::.|::.|||:|:|.|:.:::|:..:||::.|||:||..:||:.:| ||:...:|. |.....|
  Fly   113 ILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVC 177

  Fly   113 LFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFG 177
            ...::|..:....|:..|:.:|.|||:::..|:.|.....|..|..:|...|....::....::.
  Fly   178 DTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYS 242

  Fly   178 W-HADVNH---NQECLFVEVMDYN-YLVF------LYFATIITPALLMLAFYTHIYRVIIKQVRQ 231
            | :.:...   ..|| :::.::.| |:.|      .||     |..:|...|..|:|...|:.:.
  Fly   243 WPYIEGKRTVPKDEC-YIQFIETNQYITFGTALAAFYF-----PVTIMCFLYWRIWRETKKRQKD 301

  Fly   232 IVTMNPA-SDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIP 295
            :..:... .|.|:||:::..........|......:|.|...
  Fly   302 LPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDH----------------------- 343

  Fly   296 LYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQ 360
                        |.:..|:            |..:|                            .
  Fly   344 ------------DTWRRPR------------SESSP----------------------------D 356

  Fly   361 AEAIHRFSV---ASQHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVVSPCF 422
            ||:::..::   :..|.:.|..|:::||                  ..:|.|.         .||
  Fly   357 AESVYMTNMVIDSGYHGMHSRKSSIKST------------------NTIKKSY---------TCF 394

  Fly   423 NNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPGSQRSSERNSSSTVPPAPPA 487
            .:|.:                |.|....||.|
  Fly   395 GSIKE----------------WCIAWWHSGRE--------------------------------- 410

  Fly   488 PAKPSVPSASYDNHNYSFSQDEDEDDDDLEFEDVFVPASSVPNPVQPGIDPVELRRSLALVMREK 552
                       |:.::::.|:|..|..       :....::..|:|..:.    |.:...|||
  Fly   411 -----------DSDDFAYEQEEPSDLG-------YATPVTIETPLQSSVS----RCTSMNVMR-- 451

  Fly   553 LRSDDTDSRPMGNNQDLPIDEQSRERP---LSTQTSPTNGPLPALLRAKLLAGNSNSAHCLPGST 614
                  |:..||.:       .|..||   |.:..|||..|.|.|.....|...|    .:..||
  Fly   452 ------DNYSMGGS-------VSGVRPPSILLSDVSPTPLPRPPLASISQLQEMS----AVTAST 499

  Fly   615 ASPAPQEQSGIFVIDSEASPGSNGHKPKYRKGTAFTRSSLKKSRSCNCSSI---AKGRGVHDEP- 675
            .:......:|...|::..:...||:            .::..:.:.|.|.|   ..|...|.:.
  Fly   500 TANVNTSGNGNGAINNNNNASHNGN------------GAVNGNGAGNGSGIGLGTTGNATHRDSR 552

  Fly   676 ---------SSNLCRDQESSV---LPQHPQPANHPTENFFSP----LRSVGSFMQHSNLFHFLQP 724
                     |.::.:|...::   ||.....:|........|    ..|....||..........
  Fly   553 TLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMI 617

  Fly   725 HAARPTSSTA----SSTASTPTPSPPPMGQAQEESVPVG 759
            |...||::.|    :|.|:|..|.|   .:..|.|:|:|
  Fly   618 HEDGPTTTAAAAPLASAAATRRPLP---SRDSEFSLPLG 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	47/180 (26%)
		7tm_1	58..334	CDD:278431	60/289 (21%)
mAChR-A	NP_523844.2	7tm_4	117..>241	CDD:304433	36/123 (29%)
		7tm_1	121..>314	CDD:278431	50/198 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910