Protein Alignment AdoR and 5-HT1B

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 107/510 - (20%)
• Similarity: 161/510 - (31%)
• Gaps: 215/510 - (42%)

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAIL--ASMGLPRNLHAC 112
            |:.:|:|||||.||.....||.|:...||.:.|||:|||.|..|.:|...:  .|.|.......|
  Fly    99 LMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELC 163

  Fly   113 LFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMC-WVAGTIVGFLPLF 176
            ....|..|:.||.||..|||::.||||.:. .:.|: |:||...:|::..| |.|..||...|.|
  Fly   164 DIWTSCDVLCCTASILHLVAIAADRYWTVT-NIDYN-NLRTPRRVFLMIFCVWFAALIVSLAPQF 226

  Fly   177 GWHADVNH-----NQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVR------ 230
            || .|.::     .|.|:..:  |..|.:|....|...|.|::|..|..||.:..|:::
  Fly   227 GW-KDPDYMKRIEEQHCMVSQ--DVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKS 288

  Fly   231 ----------------------------------------------------------------- 230
                                                                             
  Fly   289 FNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFGRNTN 353

  Fly   231 ------------------------------------------------QIVTMNPASDLSRRSSA 247
                                                            ::.|::..:|..|.|:|
  Fly   354 TANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDADDYRTSNA 418

  Fly   248 --------------------------------------AVVQVTTP------GRGGHTGTMLRVL 268
                                                  ..:..|||      |.|...|.:....
  Fly   419 NEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAVAGGS 483

  Fly   269 GAA---------------------------------------RKRDVKATQNLSIIVLFFMICWI 294
            |:.                                       .||:.||.|.|:||...|:|||:
  Fly   484 GSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWL 548

  Fly   295 PLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLL 349
            |.:.:....:.|.:|.:|..:....:.|.:.||.:|||:|.....:||.|.|.:|
  Fly   549 PFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRIL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	63/175 (36%)
		7tm_1	58..334	CDD:278431	97/485 (20%)
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	63/185 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910