Protein Alignment AdoR and HTR4

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001035263.1
• Gene: HTR4 / 3360
• HGNCID: 5299
• Length: 428
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 107/349 - (30%)
• Similarity: 163/349 - (46%)
• Gaps: 51/349 - (14%)

  Fly    29 DAKDSDSPSSE-----LNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRR-RTNYYIVSLAMAD 87
            |..|::..|.|     ..:....|...|.:::|:||:||::....:|:||: :|||:|||||.||
Human     2 DKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFAD 66

  Fly    88 LLVGALGIPFAILASMGLPRNLHA-----CLFTVSLLVVLCTISIFCLVAVSVDRYWAI-LYPMA 146
            |||..|.:||   .::.|.:::..     ||...||.|:|.|.|||.|..:|:|||:|| ..|:.
Human    67 LLVSVLVMPF---GAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLV 128

  Fly   147 YSRNVRTRTAIFIISMCWVAGTIVGFLPLF-GWH----------ADVNHNQE---CLFVEVMDYN 197
            |...:.......::..|||..|.:.|||:. ||:          ...|.|..   |:|  :::..
Human   129 YRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVF--MVNKP 191

  Fly   198 YLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMN--PASDLSRRSSAAVVQVTTPGRGGH 260
            |.:.........|.|||:..|..||....:...||..:.  .||..||..||          ..|
Human   192 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSA----------DQH 246

  Fly   261 TGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHL 325
            :...:|.       :.||.:.|.||:..|.:||.|.:..|.:..|. |..|..::....:.|.::
Human   247 STHRMRT-------ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFI-DYTVPGQVWTAFLWLGYI 303

  Fly   326 NSAVNPVLYAYHLKDFRAALKNLL 349
            ||.:||.|||:..|.||.|...:|
Human   304 NSGLNPFLYAFLNKSFRRAFLIIL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	63/188 (34%)
		7tm_1	58..334	CDD:278431	92/298 (31%)
HTR4	NP_001035263.1	7tm_1	36..312	CDD:278431	92/298 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910