| Sequence 1: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000612.1 | Gene: | HTR2A / 3356 | HGNCID: | 5293 | Length: | 471 | Species: | Homo sapiens |
| Alignment Length: | Identity: | / - (0%) | |
|---|---|---|---|
| Similarity: | / - (0%) | Gaps: | / - (0%) |
- Green bases have known domain annotations that are detailed below.
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | |
| 7tm_1 | 58..334 | CDD:278431 | |||
| HTR2A | NP_000612.1 | 7tmA_5-HT2A | 75..391 | CDD:341345 | |
| TM helix 1 | 77..101 | CDD:341345 | |||
| TM helix 2 | 110..132 | CDD:341345 | |||
| TM helix 3 | 149..171 | CDD:341345 | |||
| Agonist binding. /evidence=ECO:0000250|UniProtKB:P41595 | 155..160 | ||||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250|UniProtKB:P41595 | 172..174 | ||||
| TM helix 4 | 194..210 | CDD:341345 | |||
| TM helix 5 | 232..255 | CDD:341345 | |||
| TM helix 6 | 322..344 | CDD:341345 | |||
| Agonist binding. /evidence=ECO:0000250|UniProtKB:P41595 | 336..340 | ||||
| TM helix 7 | 359..384 | CDD:341345 | |||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250|UniProtKB:P41595 | 376..380 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 450..471 | ||||
| PDZ-binding. /evidence=ECO:0000269|PubMed:11150294, ECO:0000269|PubMed:14988405 | 469..471 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||