DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and HTR1E

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_000856.1 Gene:HTR1E / 3354 HGNCID:5291 Length:365 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433
7tm_1 58..334 CDD:278431
HTR1ENP_000856.1 7tmA_5-HT1E 23..355 CDD:320457
TM helix 1 24..50 CDD:320457
TM helix 2 57..83 CDD:320457
TM helix 3 95..125 CDD:320457
Agonist binding. /evidence=ECO:0000250 98..107
DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 119..121
TM helix 4 137..159 CDD:320457
TM helix 5 179..208 CDD:320457
TM helix 6 284..314 CDD:320457
Agonist binding. /evidence=ECO:0000250 304..308
TM helix 7 323..348 CDD:320457
NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 340..344
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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