DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and CG32547

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001259682.1	Gene:	CG32547 / 3346150	FlyBaseID:	FBgn0052547	Length:	1008	Species:	Drosophila melanogaster

Alignment Length:	808	Identity:	143/808 - (17%)
Similarity:	270/808 - (33%)	Gaps:	261/808 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIG---NVLVIIVFRRERKLRRRTN 77
            ||:|                 .|.:...|.:|.:..|.::::|   ||::::.....|..:..|:
  Fly    90 GPIL-----------------KSSIKSVYWLFLIQYAALALLGVVLNVIIVVYIMYHRLYKDVTH 137

  Fly    78 YYIVSLAMADLLVGALGIPFAILASMGLPRN----LHACLFTVSLLVVLCTISIFCLVAVSVDRY 138
            .:|::||:...:..||.:|.:::..  |.:|    ...|.|...|..:...:::...:.::.||.
  Fly   138 AFIINLALCHFVQCALVLPVSLMVM--LIQNWIFGQFLCFFLPMLQDIPLHVAMISHILIAWDRM 200

  Fly   139 WAILYPMAYSRNVRTRTAIFIISMC-WVAGTIVGF-LPLFGWHADVNHNQECLFVEVMDY----- 196
            ..:..|:      :.|...|:.... |:.|.::.. .|::           .::||:.||
  Fly   201 RWLNDPL------KGRLPGFVCCCATWLTGMVIALPYPIY-----------TIYVELGDYMPQLS 248

  Fly   197 --------------NYLVFLYFATIITPALLMLAFYTHIYRVIIKQVR------QIVTMNPASDL 241
                          .|...|:......||:|:    :::|....:::|      .::.....:||
  Fly   249 GIGLCVVNLMDDMQEYTRGLFLLMYCGPAILL----SYLYIRTSQELRPPDGPFAVMMYEHRADL 309

  Fly   242 ---SRRSSAAVVQVTTPGRGGHTGTMLRVLGAARK-----------RDVKATQNLSIIVLFFMIC 292
               .|.||.:.|:......||..|.......:||.           |:.:..:|...:....::|
  Fly   310 RMRQRNSSTSSVEPRHLSGGGVAGLSNGGGNSARSYDLYSAELDVHREKRKQRNFGSMAATQVVC 374

  Fly   293 WIPLYTINCIKAFCPDCYVHPK----LTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMM 353
            ..||..:...:....:.|.:.|    ..|..:.::.|.:.:.|.:||..:
  Fly   375 MCPLMILRFARLSLEETYENAKHFDFTYLMFVWVAFLPTVIFPCIYASQI--------------- 424

  Fly   354 GVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVV 418
             :..|:|......|.::|:.:.:|        |.|...|..|.:....::::::..:
  Fly   425 -LPRDEQERLRGYFRLSSKRKQKS--------QRRSDAGGGSGVGGSSREDSIEKDE-------- 472

  Fly   419 SPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPGSQRSSERNSSSTVPP 483
                          ||.||.:.    :..|....:.......|...|..||....:|.:.
  Fly   473 --------------ASNTTSVH----HAAEPHKHSSKLRHEREVRLPGHGSSAGGDRYTG----- 514

  Fly   484 APPAPAKPSVPSASYDNHNYSFSQDED-EDDDDLEFEDVFVPASSVPNPVQPGIDPVELRRSLAL 547
            ||....|         :......:|.| |.|.|.|.|
  Fly   515 APYRQGK---------DRERERERDRDRERDRDRERE---------------------------- 542

  Fly   548 VMREKLRSDDTDSRPMGNNQDLPIDEQSRERPLSTQTSPTNGPLPALLRAKLLAGNSNSAHCLPG 612
              ||:.|:....:...|...:|..|.:.::..:..... ::|           .|:..::|   .
  Fly   543 --RERQRAGGRGAGDAGVVNNLGKDVRGKKHDVKINII-SDG-----------VGHGATSH---S 590

  Fly   613 STASPAPQEQSGIFVIDSEASPGSNGH---------KPKYRKG----TAFTRSSLKKSRSCNCS- 663
            ..|.||.::|:|          |:|.:         .|..|.|    ||...|::..|..||.|
  Fly   591 HAAHPAHRKQTG----------GNNNNNNNSSRSRTNPGQRHGGSKLTADCLSNVTASTFCNGSG 645

  Fly   664 SIAKG--------RGV---HDEPSSNLCRDQESSVLPQHPQPANHPTENFFSPLR---SVGSFMQ 714
            |:..|        .||   .|..:||....:||||:.....|          |.|   |.|..::
  Fly   646 SVTAGATGNGNGPSGVLIPDDSSTSNYGDGEESSVVSSMMVP----------PQRWPGSGGGVLR 700

  Fly   715 HSNLFHFLQPHAARPTSSTASSTASTPT 742
            |.::           :.|..|||.|:.|
  Fly   701 HKDV-----------SFSECSSTFSSST 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	34/195 (17%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	56/327 (17%)
CG32547	NP_001259682.1	7TM_GPCR_Srd	104..>195	CDD:304638	18/92 (20%)
CG32547	NP_001259682.1	7tm_1	119..>292	CDD:278431	33/195 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910