Protein Alignment AdoR and Dop2R

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001014758.2
• Gene: Dop2R / 33007
• FlyBaseID: FBgn0053517
• Length: 905
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 109/531 - (20%)
• Similarity: 181/531 - (34%)
• Gaps: 241/531 - (45%)

  Fly    49 VLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAIL----ASMGLPRNL 109
            :|..|:::.||:|||:...|||.|:..|||:|||||:|||||..:.:|||:.    .:..||..:
  Fly   383 ILFPILTLFGNILVILSVCRERSLQTVTNYFIVSLAIADLLVAVVVMPFAVYFLVNGAWALPDVV 447

  Fly   110 HACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLP 174
              |.|.:::.|:..|.|||.|||:|:|||.|:..|:.|:::..:|.....|.:.|.....:|...
  Fly   448 --CDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNSRRVCLTILLVWAISAAIGSPI 510

  Fly   175 LFGWHADVNHNQE-CLFVEVMDYN--YLVFLYFATIITPALLMLAFYTHIYRVI----------- 225
            :.|.:...|...: |.|     ||  ::::...::...|.::|:..|.:|::.:
  Fly   511 VLGLNNTPNREPDVCAF-----YNADFILYSSLSSFYIPCIIMVFLYWNIFKALRSRARKQRAAR 570

  Fly   226 ---------------IKQVRQIVTMNPASDLSRRSS----------------------------- 246
                           |.|.|::.  ..|.|.||.:|
  Fly   571 KPHLSELTGGSVIENIAQTRRLA--ETALDSSRHASRILPDEAATNTASGSNEEEDENAISPDID 633

  Fly   247 ------------------------AAVVQVTTPGR-------GGH-------------------- 260
                                    :.|.|:||..:       |.|
  Fly   634 DCHVIVNDKSTEFMLATVVEETGNSVVAQITTQPQLVVADPNGNHDSGYAASNVDDVLAGVAPAS 698

  Fly   261 -------------------------------------TG--------TMLRVLG----------- 269
                                                 ||        ..||.:|
  Fly   699 ASAATSAAPRSSGSPPDSPLPSGATLQRSSVSSQRRPTGDDSPKRGEPALRSVGVDNSSVAMKPL 763

  Fly   270 -------------------------------------------------------AARKRDVKAT 279
                                                                   ::.|::.|||
  Fly   764 SFVRYGVQEAMTLARNDSTLSTTSKTSSRKDKKNSQASRFTIYKVHKASKKKREKSSAKKERKAT 828

  Fly   280 QNLSIIVLFFMICWIPLYTINCIKAFC----PDCYVHPKLTLFCII--LSHLNSAVNPVLYAYHL 338
            :.|:|::..|:.||:|.::.|.:.|.|    .||  .|.||.:.:.  |.::||.||||:|....
  Fly   829 KTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDC--RPGLTAYMMTTWLGYINSFVNPVIYTIFN 891

  Fly   339 KDFRAALKNLL 349
            .:||.|.|.::
  Fly   892 PEFRKAFKKIM 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	58/174 (33%)
		7tm_1	58..334	CDD:278431	102/505 (20%)
Dop2R	NP_001014758.2	7tmA_D2-like_dopamine_R	376..>565	CDD:320181	60/188 (32%)
		TM helix 1	377..403	CDD:320181	7/19 (37%)
		TM helix 2	410..436	CDD:320181	16/25 (64%)
		TM helix 3	448..478	CDD:320181	15/29 (52%)
		TM helix 4	490..513	CDD:320181	4/22 (18%)
		TM helix 5	529..558	CDD:320181	5/28 (18%)
		7tm_GPCRs	<822..898	CDD:333717	28/77 (36%)
		TM helix 6	825..850	CDD:320095	9/24 (38%)
		TM helix 7	866..891	CDD:320095	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910