Protein Alignment AdoR and S1pr3

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001258072.1
• Gene: S1pr3 / 306792
• RGDID: 1583843
• Length: 379
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 104/424 - (24%)
• Similarity: 169/424 - (39%)
• Gaps: 95/424 - (22%)

  Fly    34 DSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFA 98
            |.|.....|...:|.|..:.: ::.|::|:|...:..|...|..::|.:||:.|||.| :.....
  Rat    34 DPPEGSTLITTILFLVTCSFI-VLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAG-IAYKVN 96

  Fly    99 ILASMGLPRNLHACLFTV---SLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFII 160
            ||.|.....:|...::.:   |:.|.| ..|...|:|::::|:..::....|..|.:.| ...:|
  Rat    97 ILMSGRKTFSLSPTVWFLREGSMFVAL-GASTCSLLAIAIERHLTMIKMRPYDANKKHR-VFLLI 159

  Fly   161 SMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYNYLVFL---YFATIITPALLMLAFYTHIY 222
            .|||:....:|.||:.||:...|.......:.:....|:.||   :.|.::|..:|    |..||
  Rat   160 GMCWLIAFSLGALPILGWNCLENFPDCSTILPLYSKKYIAFLISIFTAILVTIVIL----YARIY 220

  Fly   223 RVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVL 287
            .::....|::...|     |.||.|                :||              .:.|:|.
  Rat   221 FLVKSSSRRVANHN-----SERSMA----------------LLR--------------TVVIVVS 250

  Fly   288 FFMICWIPLYTINCIKAFC--PDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNL-- 348
            .|:.||.||:.:..|...|  .:|.:..|...| |:|:.||||:|||:|....|:.|.|...|
  Rat   251 VFIACWSPLFILFLIDVACRAKECSILFKSQWF-IMLAVLNSAMNPVIYTLASKEMRRAFFRLVC 314

  Fly   349 --LLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQL 411
              |:|..|........|:      ...|.:|..||..|:        :||          |..:.
  Rat   315 GCLVKGKGTQASPMQPAL------DPSRSKSSSSNNSSS--------HSP----------KVKED 355

  Fly   412 LPKCGVVSPCFNNINQTVAAVASVTTDLEREMWN 445
            ||.               .|.:|..||..|.:.|
  Rat   356 LPH---------------VATSSCVTDKTRSLQN 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	43/173 (25%)
		7tm_1	58..334	CDD:278431	74/283 (26%)
S1pr3	NP_001258072.1	7tmA_S1PR3_Edg3	43..309	CDD:320467	79/309 (26%)
		TM helix 1	43..67	CDD:320467	5/24 (21%)
		TM helix 2	76..97	CDD:320467	7/21 (33%)
		TM helix 3	113..135	CDD:320467	6/22 (27%)
		TM helix 4	157..173	CDD:320467	5/15 (33%)
		TM helix 5	194..217	CDD:320467	6/26 (23%)
		TM helix 6	242..264	CDD:320467	9/35 (26%)
		TM helix 7	277..302	CDD:320467	12/25 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910