Protein Alignment AdoR and HCRTR2

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_016866287.1
• Gene: HCRTR2 / 3062
• HGNCID: 4849
• Length: 461
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 108/416 - (25%)
• Similarity: 183/416 - (43%)
• Gaps: 75/416 - (18%)

  Fly    49 VLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMG----LPRNL 109
            ::|.:|::||||||.:...:...:|..|||:||:|::||:||....:|..::..:.    ..::|
Human    62 IIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSL 126

  Fly   110 HACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAY-SRNVRTRTAIFIISMCWVAGTIVGFL 173
              |.....|..|..::|:..|..:::||::||.:|:.: |...|.|.:|.||   |:...|: .:
Human   127 --CKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVII---WIVSCII-MI 185

  Fly   174 P---------LFGWHADVNHNQECLFV--------EVMDYNYLVFLYFATIITPALLMLAFYTHI 221
            |         :|...|    |:..||.        |:....|.:..:..|.:.|..||:..|..|
Human   186 PQAIVMECSTVFPGLA----NKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQI 246

  Fly   222 YRVIIKQVRQIVTMNP-ASDLSRRSSAAVVQVTTP-GRGGHTGTMLRVLGA------ARKRDVKA 278
            :|.:  ..|||    | .|.:.:|....:..|:.| |.|..|.:.:..:.|      ||:   |.
Human   247 FRKL--WCRQI----PGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR---KT 302

  Fly   279 TQNLSIIVLFFMICWIPLYTINCIK-AFCPDCYVHPKLTLFC-IILSH----LNSAVNPVLYAY- 336
            .:.|.|::|.|.||::|:..:|.:| .|....:...:.|::. ...||    .|||.||::|.:
Human   303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFL 367

  Fly   337 ---HLKDFRAALKNLLLKMMGVDIDQQAEAIH-RFSVASQHRLQSMDSNMRSTQPRLYVGEYSPI 397
               ..::|:||.....|   ||...|:..... |.|..|:..|.:..||            :..|
Human   368 SGKFREEFKAAFSCCCL---GVHHRQEDRLTRGRTSTESRKSLTTQISN------------FDNI 417

  Fly   398 WLRQQQEALKNSQLLPKCGVVSPCFN 423
            ....:|..|.:...||......|..|
Human   418 SKLSEQVVLTSISTLPAANGAGPLQN 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	51/189 (27%)
		7tm_1	58..334	CDD:278431	84/311 (27%)
HCRTR2	XP_016866287.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910