Protein Alignment AdoR and P2RY8

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_006724506.2
• Gene: P2RY8 / 286530
• HGNCID: 15524
• Length: 548
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 78/341 - (22%)
• Similarity: 149/341 - (43%)
• Gaps: 77/341 - (22%)

  Fly    35 SPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAI 99
            :|:..:.:|  |...|||.|||.||:..:.|..|....|..:..::::|::.||::.:: :||.|
Human   208 NPAIAVALP--VVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASV-LPFQI 269

  Fly   100 LASMGLPRNLHACLFTVSLLVVLCTI-----------SIFCLVAVSVDRYWAILYPMAYSRNVRT 153
            ....    |.|..:|.    |:||.:           ||..:..:||:|:..:|||::..|..|.
Human   270 YYHC----NRHHWVFG----VLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRR 326

  Fly   154 RTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFV----EVMDYNYLVFLYFATIITPALLM 214
            |.|:...:..|:. .:....||.  ..|:.:....|.:    :|:.:..|          |::.|
Human   327 RYAVAACAGTWLL-LLTALSPLA--RTDLTYPVHALGIITCFDVLKWTML----------PSVAM 378

  Fly   215 LAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVL------GAARK 273
            .|.:.....:::..:..::|:                      ..:|.|:|::|      |..::
Human   379 WAVFLFTIFILLFLIPFVITV----------------------ACYTATILKLLRTEEAHGREQR 421

  Fly   274 RDVKATQNLSIIVLFFMICWIP----LYTINCIKAFCPDCYVHP-KLTLFCIILSHLNSAVNPVL 333
            |  :|....::::|.|:.|:.|    |......:.|....|.|. |||| |  ||.||:.::|.:
Human   422 R--RAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTL-C--LSCLNNCLDPFV 481

  Fly   334 YAYHLKDFRAALKNLL 349
            |.:..::|:..|:..|
Human   482 YYFASREFQLRLREYL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	43/182 (24%)
		7tm_1	58..334	CDD:278431	65/301 (22%)
P2RY8	XP_006724506.2	7tm_4	222..>321	CDD:304433	30/107 (28%)
		7tm_1	229..482	CDD:278431	65/301 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910