Protein Alignment AdoR and GPR19

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_011518925.1
• Gene: GPR19 / 2842
• HGNCID: 4473
• Length: 434
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 77/322 - (23%)
• Similarity: 135/322 - (41%)
• Gaps: 68/322 - (21%)

  Fly    45 TVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNL 109
            ::|..::.:.||.||.||.:|..|.|:.:..|||::||:|.||||:.....||.:|.
Human    88 SIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQ-------- 144

  Fly   110 HACLFTV---SLLVVLCT-----------ISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFII 160
                ||.   :|....|.           :.|:.|:::.:||::.|:||:::  .|....|..:|
Human   145 ----FTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSF--KVSREKAKKMI 203

  Fly   161 SMCWV--AGTIVGFLPLFGWHADVNHNQECLFVEVMDYN---YLVFLYFATIITPALLMLAFYTH 220
            :..||  ||.:...|..:|    .|.:..|.:.....:.   |.|..:....:.|::|::.||..
Human   204 AASWVFDAGFVTPVLFFYG----SNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQK 264

  Fly   221 IYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSII 285
            :.:.|.:                        :.|.||     |:.|.:....:..||..:...|:
Human   265 VIKYIWR------------------------IGTDGR-----TVRRTMNIVPRTKVKTIKMFLIL 300

  Fly   286 VLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCII-LSHLNSAVNPVLYAYHLKDFRAALK 346
            .|.|::.|:|.:..........| |....|....|. :|..:||..|.||:.:..:||..:|
Human   301 NLLFLLSWLPFHVAQLWHPHEQD-YKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMK 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	50/186 (27%)
		7tm_1	58..334	CDD:278431	69/295 (23%)
GPR19	XP_011518925.1	7tm_4	91..>277	CDD:304433	52/227 (23%)
		7tm_1	101..349	CDD:278431	69/295 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910