DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdoR and adra2a

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_997520.3 Gene:adra2a / 266750 ZFINID:ZDB-GENE-021010-1 Length:388 Species:Danio rerio


Alignment Length:380 Identity:103/380 - (27%)
Similarity:163/380 - (42%) Gaps:91/380 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 IPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASM--- 103
            :|.:|...|:.::.|.|||||||.....|.||...|.::||||.||:||..|.:||::...:   
Zfish    23 LPLSVAVGLLILLIIFGNVLVIIAVFTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMGM 87

  Fly   104 ----GLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRN---VRTRTAIFIIS 161
                |:     .|...::|.|:.||.||..|.|:|:||||:|...:.|:..   .|.:..|||: 
Zfish    88 WTFGGV-----WCEIYLALDVLFCTASITHLCAISLDRYWSITQAIEYNLKRTPQRIKRIIFIV- 146

  Fly   162 MCWVAGTIVGFLPLF------GWHADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTH 220
              |:...::...||.      |...|:|..:.          |:|.....:...|.::|:..|..
Zfish   147 --WIIAAVISCPPLITMKKSEGDICDINKEKW----------YIVSSCIGSFFLPCIIMVLVYIR 199

  Fly   221 IYRVIIKQVR----------------------------------QI--VTM-----------NPA 238
            ||::..|:.|                                  :|  |.|           ||.
Zfish   200 IYQIAKKRTRAPPGDHRKNEVGKKENDPHEKLNGIQNAEPDDKDEINGVDMEESSSSDHKVSNPC 264

  Fly   239 SDLSRRSSAAVVQVT--TPGRGGHTGTMLRVLGAAR-----KRDVKATQNLSIIVLFFMICWIPL 296
            | |.::||....:::  .||.|..| ...:...|:|     .|:.:.|..|::::..|:|||.|.
Zfish   265 S-LKKKSSKGKTKLSQIKPGDGDKT-EACQTTKASRWKGRQNREKRFTFVLAVVIGVFVICWFPF 327

  Fly   297 YTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLK 351
            :......||| ||.|...|..|.....:.||::||::|.....|||.:.|.:|.:
Zfish   328 FFTYTFTAFC-DCCVPETLFKFFFWFGYCNSSLNPIIYTIFNNDFRRSFKKILCR 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 55/183 (30%)
7tm_1 58..334 CDD:278431 93/345 (27%)
adra2aNP_997520.3 7tm_4 31..>165 CDD:304433 48/141 (34%)
7tm_1 39..364 CDD:278431 93/345 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 208..291 14/84 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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