Protein Alignment AdoR and ser-3

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_491954.1
• Gene: ser-3 / 259744
• WormBaseID: WBGene00004778
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 118/571 - (20%)
• Similarity: 187/571 - (32%)
• Gaps: 239/571 - (41%)

  Fly    45 TVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPR-- 107
            :|..|||.:| ::||.|||......|:||..|...|:|||:||||||.:.:||:| |:..|.:
 Worm    63 SVLTVLVVVV-VLGNALVIAAVLLRRRLRSATGLLILSLALADLLVGTVILPFSI-ANEVLDQYW 125

  Fly   108 --NLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIV 170
              ....|...::|.:.:||.||:.|||:|:|||.||:.|:.|...|....|...:::.|: |:.:
 Worm   126 IFGETWCTIWLTLDIWMCTASIYNLVAISIDRYIAIIKPLNYPMLVTKFRARCTVAIVWI-GSFL 189

  Fly   171 GFLPLFGWHADVNHNQ---ECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIY---RVIIKQV 229
            ...|.|...:.:...:   .|..... ...|:||...::...|.::::..|..||   |...|.:
 Worm   190 ICSPSFFLASSIKDKETPCRCTPANA-GRVYVVFSASSSFYIPMIIVVFVYFRIYVAARAATKSI 253

  Fly   230 ---RQIVT------MNPASDL----------------SRRSSAAVVQVT---------------- 253
               ...||      .||.|.|                ..|.|:.|.|:|
 Worm   254 YSGMMSVTAAANKKQNPKSYLLNHPDVINKDSLPMLRVHRGSSVVAQITPNKPYNTCRQNGNSID 318

  Fly   254 ----------------------------------------------------------------- 253
                                                                             
 Worm   319 ATANGTSQITAAATKARKFANDSAKTLVNRGAVGATQQAPIGARFKRHGRDSESSVDSMNGTNSY 383

  Fly   254 --TPGRGGH-------------------------------------------------------- 260
              ||.:.|:
 Worm   384 SATPHKSGNEELGSLIENSRSSSTDSNEKTEQLTNQTDDNFSMSNNNNNGDEKEAFDESLLSESK 448

  Fly   261 ---------------TGTMLRVLGAARKR---DVKATQNLSIIVLFFMICWIPLYTINCIKAFCP 307
                           .|...|..||..||   ::||.:.::|:...|:.||:....:..::....
 Worm   449 KKSKSLASKFNHLMRRGQKKRTAGAYEKRLSLEIKAAKTVAIVTGCFIFCWLGFALVYGLEIKLN 513

  Fly   308 DCYVHPKLTLFCII--LSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVA 370
            |       .::.|:  |.:||||:|||:|....::||...|.||             ..|..:
 Worm   514 D-------VVWSIVFWLGYLNSALNPVIYTVFNREFRICFKRLL-------------TCHHLN-- 556

  Fly   371 SQHRLQSMDSN-------MRSTQ-----PRLYVGEYSPIWLRQQQEALKNS 409
              |..|...:|       :|||.     |:..:|.|:     |.|.:.|:|
 Worm   557 --HPTQKYTNNNSYNSTAIRSTNAVNRVPQTSLGNYT-----QTQNSEKSS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	54/174 (31%)
		7tm_1	58..334	CDD:278431	93/469 (20%)
ser-3	NP_491954.1	7tmA_Octopamine_R	80..>252	CDD:320191	52/174 (30%)
		TM helix 2	94..116	CDD:320191	12/21 (57%)
		TM helix 3	133..155	CDD:320191	8/21 (38%)
		TM helix 4	178..194	CDD:320191	2/16 (13%)
		TM helix 5	217..240	CDD:320191	4/22 (18%)
		7tm_GPCRs	<479..546	CDD:391938	19/73 (26%)
		TM helix 6	479..509	CDD:341315	6/29 (21%)
		TM helix 7	514..539	CDD:341315	11/31 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910