Protein Alignment AdoR and Adora3

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001289684.1
• Gene: Adora3 / 25370
• RGDID: 2051
• Length: 337
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 110/387 - (28%)
• Similarity: 177/387 - (45%)
• Gaps: 85/387 - (21%)

  Fly    30 AKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALG 94
            |.::.:.:..|.|.|...|..:.:.:::||:|||.|.:..|.||..|.|:|||||:||:.||.|.
  Rat     3 ANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLV 67

  Fly    95 IPFAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYS----------- 148
            ||.||..|:.:..:.:||||...:|:|....||..|:|::||||..:...:..|
  Rat    68 IPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRLSFLVVNLPFSSP 132

  Fly   149 -----RNVRTRTAIFI-ISMCWVAGTIVGFLPLFGWHADV-------NHNQECLFVEVMDYNYLV 200
                 |.|.|:..|:: :.:||:...:||..|:|||:..|       :....|.|..|:..:|:|
  Rat   133 HSNRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV 197

  Fly   201 FLYFAT-IITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTM 264
            |..|.| |:.|.::|...|..|:.:|..::.|.:                             |.
  Rat   198 FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNL-----------------------------TG 233

  Fly   265 LRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFC--IILSHLNS 327
            .|...|...|:.|..::|.:::..|.:||:||..||.:..|....   |::.: |  |:|||.||
  Rat   234 FRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKI---PEIAM-CLGILLSHANS 294

  Fly   328 AVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRL----QSMDSNMRST 385
            .:||::||..:|.|:...                     |.:....||    .|:|||:..|
  Rat   295 MMNPIVYACKIKKFKETY---------------------FVILRACRLCQTSDSLDSNLEQT 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	66/192 (34%)
		7tm_1	58..334	CDD:278431	93/302 (31%)
Adora3	NP_001289684.1	7tm_4	23..>126	CDD:304433	41/102 (40%)
		7tm_1	31..301	CDD:278431	93/302 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344430
Domainoid	1	1.000	174	1.000	Domainoid score	I3568
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	1	1.000	-	-		otm45013
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24246
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.940