| Sequence 1: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036984.1 | Gene: | Htr1d / 25323 | RGDID: | 2847 | Length: | 374 | Species: | Rattus norvegicus |
| Alignment Length: | 380 | Identity: | 109/380 - (28%) |
|---|---|---|---|
| Similarity: | 170/380 - (44%) | Gaps: | 51/380 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 SITDFSFEGPLLPLHAATTSKDAKDSDSPS--SELNIPYTVFEVLVAIVSIIGNVLVIIVFRRER 70
Fly 71 KLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLH--ACLFTVSLLVVLCTISIFCLVAV 133
Fly 134 SVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQ--ECLFVEVMDY 196
Fly 197 NYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRG--- 258
Fly 259 ---------GHTGTM-------------------LRVLGAARKRDVKATQNLSIIVLFFMICWIP 295
Fly 296 LYTINCIKAFCPD-CYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLL 349 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | 49/171 (29%) |
| 7tm_1 | 58..334 | CDD:278431 | 91/311 (29%) | ||
| Htr1d | NP_036984.1 | 7tmA_5-HT1B_1D | 32..364 | CDD:320455 | 98/342 (29%) |
| TM helix 1 | 38..62 | CDD:320455 | 3/23 (13%) | ||
| TM helix 2 | 71..93 | CDD:320455 | 12/21 (57%) | ||
| TM helix 3 | 109..131 | CDD:320455 | 7/21 (33%) | ||
| Agonist binding. /evidence=ECO:0000250 | 111..120 | 2/8 (25%) | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 132..134 | 1/1 (100%) | |||
| TM helix 4 | 154..170 | CDD:320455 | 2/15 (13%) | ||
| TM helix 5 | 192..215 | CDD:320455 | 3/22 (14%) | ||
| TM helix 6 | 297..319 | CDD:320455 | 9/21 (43%) | ||
| Agonist binding. /evidence=ECO:0000250 | 311..315 | 2/3 (67%) | |||
| TM helix 7 | 332..357 | CDD:320455 | 11/24 (46%) | ||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 349..353 | 3/3 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||