Protein Alignment AdoR and Drd5

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_036900.1
• Gene: Drd5 / 25195
• RGDID: 2523
• Length: 475
• Species: Rattus norvegicus
• Alignment Length: 438
• Identity: 111/438 - (25%)
• Similarity: 186/438 - (42%)
• Gaps: 86/438 - (19%)

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLR-RRTNYYIVSLAMADLLVGALGIPFAILASMG--LPRNLHA 111
            |:.:.:::|||||.....|.|.|| :.||.:|||||::||.|..|.:|:..:|.:.  .|....
  Rat    47 LLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTF- 110

  Fly   112 CLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPL- 175
            |...|:..::..|.||..|..:||||||||..|..|.|.:..|.|:.::.:.|....::.|:|:
  Rat   111 CDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQ 175

  Fly   176 FGWHADV--NHNQECLFV-------------------EVMDYNYLVFLYFATIITPALLMLAFYT 219
            ..||.|.  :..||.|..                   ..::..|.:.....:...|..:|:..||
  Rat   176 LNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYT 240

  Fly   220 HIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSI 284
            .|||:...|:|:|.::..|::.::...:.......|.           |.|:.|::.|..:.||:
  Rat   241 RIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPS-----------LRASIKKETKVFKTLSM 294

  Fly   285 IVLFFMICWIPLYTINCIKAFCPD-----------CYVHPKLTLFCIILSHLNSAVNPVLYAYHL 338
            |:..|:.||:|.:.:||:..||..           |.......:| :.....||::||::||::
  Rat   295 IMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIF-VWFGWANSSLNPIIYAFN- 357

  Fly   339 KDFRAALKNLL--------LKMMGVDID------QQAEAIHR-FSVASQHRL-QSMDSNMRST-- 385
            .|||.....||        ..:..|:|.      .|....|: .:.|..|.: .::.|..|..
  Rat   358 ADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGE 422

  Fly   386 ----QPRLYVGEYSP-----------IWLRQQQEAL---KNSQLLPKC 415
                .|..::.:.||           :|....:|.:   |.|.|.|.|
  Rat   423 EEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNC 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	55/192 (29%)
		7tm_1	58..334	CDD:278431	85/311 (27%)
Drd5	NP_036900.1	7tm_1	55..354	CDD:278431	85/311 (27%)
		7tm_4	<121..>173	CDD:304433	19/51 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..443		5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910