DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and GPR161

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:XP_006711316.2 Gene:GPR161 / 23432 HGNCID:23694 Length:609 Species:Homo sapiens


Alignment Length:376 Identity:83/376 - (22%)
Similarity:161/376 - (42%) Gaps:45/376 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FRYFSITDFSFEGPLLPLHAATTSKDAKDSDSPSSELN-------------------IPYTVFEV 49
            |:.||.:.....|..:..||..|.:....:.|.:|.|:                   |...:..:
Human    51 FKQFSASASPVAGTTVVQHALPTPRRGALTMSLNSSLSCRKELSNLTEEEGGEGGVIITQFIAII 115

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASM------GLPRN 108
            ::.|...:||:::::...::..|...:|.::.||.:::.|:..|.:||.:.:|:      |:.  
Human   116 VITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVV-- 178

  Fly   109 LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFL 173
              .|.|:..|.:::.:.|:..|..:::|||:|:||||.|...:....|:..:...|:...|....
Human   179 --WCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLP 241

  Fly   174 PLFGWHADVNHNQ---ECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQ---- 231
            ||||| :.|..::   .|:.....:..|..|......:.|.|:||..|..|:||...:.|:    
Human   242 PLFGW-SSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCG 305

  Fly   232 --IVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWI 294
              ::....|....|::|:    .:|...|........|:.:|.:  .||...:.:::..||:.|.
Human   306 TVVIVEEDAQRTGRKNSS----TSTSSSGSRRNAFQGVVYSANQ--CKALITILVVLGAFMVTWG 364

  Fly   295 PLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAAL 345
            |...:...:|......|.|.|..:...||..::..:|::|....|..|..|
Human   365 PYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKEL 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 44/176 (25%)
7tm_1 58..334 CDD:278431 67/290 (23%)
GPR161XP_006711316.2 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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