Protein Alignment AdoR and npr-13

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_506659.2
• Gene: npr-13 / 191160
• WormBaseID: WBGene00013883
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 115/481 - (23%)
• Similarity: 189/481 - (39%)
• Gaps: 132/481 - (27%)

  Fly    39 ELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFA-ILAS 102
            |:.:.|:|...|:.|:.::||.|:|......:|| ...|.::::||::|||:....:|.. :||.
 Worm    27 EVRLGYSVLYFLILIIGLVGNGLLITSILMRKKL-SVANIFLINLAVSDLLLCITAVPITPVLAF 90

  Fly   103 MGLPRNLHACLFTVSL--LVVLC-----TISIFCLVAVSVDRY-----------------WAIL- 142
            |      ...:|.:.:  ||..|     .||.:.|..:::|||                 |.::
 Worm    91 M------KRWIFGIIMCKLVPTCQAFSVLISSWSLCYIAIDRYRSIVTPLREPWSDRHARWLLMF 149

  Fly   143 ---------YPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYNY 198
                     ||:.||:|::|    .:|....:.|...|   .|.|.:|          |:....|
 Worm   150 TWVVAFLASYPLYYSQNLKT----MVIENVTLCGDFCG---EFNWQSD----------EISKLTY 197

  Fly   199 LVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGT 263
            ...|....:|.||::|    :..|.:|:::|:....::..|.|:     |..|..|
 Worm   198 TTSLLIIQLIIPAIIM----SFCYLMILQKVQTDWLVDEGSMLT-----AAQQAQT--------- 244

  Fly   264 MLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIK------AFCPDCYVHPKLTL----- 317
                  |.|||.|...  |.::|:.||.||.||..:|..:      .||...|   |:.:
 Worm   245 ------AVRKRRVMYV--LILMVIVFMACWFPLSAVNLFRDLGMRFEFCQTVY---KVLMMDQMY 298

  Fly   318 FCIILSH---LNSAV-NPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRF------SVASQ 372
            |.::..|   :.|.| |||||.:..|..|.|||:.:..:...........:.||      ||..:
 Worm   299 FKLLNVHVIAMTSIVWNPVLYFWMSKRHRRALKDDMTWLTNARRHTNVGVLSRFTPSPSVSVVYR 363

  Fly   373 HRLQ----------------SMDSNMRSTQPRLYVGEY--SPIWLRQQQEALKNSQL-LPKCGVV 418
            ..|:                :..|..||....|....:  .|:....|....|||.| :.:.|:|
 Worm   364 RTLERHLGVNHFRRGTLADPTCTSRERSLPRELQSNCFLLVPLMPLCQSVTRKNSHLAINRDGIV 428

  Fly   419 SPCFNNINQTVAAVASVTTDLEREMW 444
            .|   ..|.:....:||.|:..|: |
 Worm   429 IP---QANGSSRRPSSVNTNSTRD-W 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	47/202 (23%)
		7tm_1	58..334	CDD:278431	79/325 (24%)
npr-13	NP_506659.2	7tmA_NPYR-like	32..330	CDD:320331	87/350 (25%)
		TM helix 1	32..56	CDD:320331	8/23 (35%)
		TM helix 2	64..86	CDD:320331	7/21 (33%)
		TM helix 3	102..124	CDD:320331	6/21 (29%)
		TM helix 4	145..161	CDD:320331	2/15 (13%)
		TM helix 5	195..218	CDD:320331	6/26 (23%)
		TM helix 6	249..274	CDD:320331	10/26 (38%)
		TM helix 7	298..323	CDD:320331	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910