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Protein Alignment AdoR and S1PR1

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001307659.1	Gene:	S1PR1 / 1901	HGNCID:	3165	Length:	382	Species:	Homo sapiens

Alignment Length:	350	Identity:	85/350 - (24%)
Similarity:	161/350 - (46%)	Gaps:	46/350 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SITDF-SFEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERK 71
            |::|: :::  ::..|...|.|....:|..:| :.:...|| :|:....|:.|:.|::...:.:|
Human    15 SVSDYVNYD--IIVRHYNYTGKLNISADKENS-IKLTSVVF-ILICCFIILENIFVLLTIWKTKK 75

  Fly    72 LRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLHACLF--TVSLLVVLCTISIFCLVAVS 134
            ..|...|:|.:||::|||.|.......:|:.....:...|..|  ..|:.|.| :.|:|.|:|::
Human    76 FHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVAL-SASVFSLLAIA 139

  Fly   135 VDRYWAILYPMAY--SRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYN 197
            ::||..:|....:  |.|.|   ...:||.|||...|:|.||:.||:. ::....|..|..:.:.
Human   140 IERYITMLKMKLHNGSNNFR---LFLLISACWVISLILGGLPIMGWNC-ISALSSCSTVLPLYHK 200

  Fly   198 YLVFLYFATIITPALL-MLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHT 261
            :.: |:..|:.|..|| ::..|..||.::..:.|::......|..||.|..::..:.|
Human   201 HYI-LFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKT------- 257

  Fly   262 GTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFC--PDCYVHPKLTLFCIILSH 324
                                :.|::..|:.||.||:.:..:...|  ..|.:..:...| ::|:.
Human   258 --------------------VIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYF-LVLAV 301

  Fly   325 LNSAVNPVLYAYHLKDFRAALKNLL 349
            |||..||::|....|:.|.|...::
Human   302 LNSGTNPIIYTLTNKEMRRAFIRIM 326

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.