Protein Alignment AdoR and srw-99

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_503487.1
• Gene: srw-99 / 189965
• WormBaseID: WBGene00005846
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 407
• Identity: 73/407 - (17%)
• Similarity: 139/407 - (34%)
• Gaps: 129/407 - (31%)

  Fly    22 HAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMA 86
            ||....:...|..:.:...|.....|.:::       |:|.:||..|:......||..::.:|.:
 Worm     6 HAGPYEQIVNDIANYAHYANFSLCCFALII-------NLLHLIVLTRKSMRTTSTNVILIGIAFS 63

  Fly    87 DL-LVGALGIPFAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRY-------W---- 139
            |: .:.|.......:..:..|.    ||.:..|..:...::::.|      :|       |
 Worm    64 DICAMSATVYKHFEMVDVENPE----CLTSNKLWKIYLNMNVWAL------QYHFRRCSSWLGVL 118

  Fly   140 --AILYPMAYSRNVRTRTA-------IFIISMCWVAGTI-------------------------- 169
              ::.|.:..|...|::.|       :||:..| |:.|:
 Worm   119 LASVRYVILKSLTDRSKFAKPKVGWKLFIVVQC-VSATLSLVYQLRFQVLEDRTIPLPISCAEFQ 182

  Fly   170 ---------VGFLPLFGWHADVNHNQECLFVEVMDYNYLV-FLYFATIITPALLMLAFYTHIYRV 224
                     :..:|||     .|:||     .|:...||| .|....:...|..:|.|:
 Worm   183 DINNASKYTLSLIPLF-----QNNNQ-----LVLRLFYLVNGLVTRDLPCGAFPILTFF------ 231

  Fly   225 IIKQVRQIVTMNPASDLSR---RSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIV 286
            :::::|:...::..|..|.   ||.|.           |                |.|:.:..:.
 Worm   232 LLRELRKTKKLDKVSHRSNTIDRSEAR-----------H----------------KTTKCIVFMT 269

  Fly   287 LFFMICWIPLYTINCIKAFC-PDCYVH---PKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKN 347
            ..:.|...|:..|:.:|.|. .|..|:   ..|.::..:|..:||..:.|:.......:|    .
 Worm   270 NAYFIAEAPMGIISLVKVFFNTDDRVYLISVDLVIYFTLLLTINSICHSVICFMMSTQYR----K 330

  Fly   348 LLLKMMGVDIDQQAEAI 364
            .:.||.|:...:..|||
 Worm   331 TIWKMFGIRKKKINEAI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	40/224 (18%)
		7tm_1	58..334	CDD:278431	61/339 (18%)
srw-99	NP_503487.1	7TM_GPCR_Srw	23..339	CDD:370978	67/380 (18%)
		TM helix 1	23..45	CDD:320109	6/28 (21%)
		TM helix 2	54..76	CDD:320109	4/21 (19%)
		TM helix 3	99..121	CDD:320109	3/27 (11%)
		TM helix 4	144..160	CDD:320109	5/16 (31%)
		TM helix 5	207..230	CDD:320109	6/22 (27%)
		TM helix 6	259..284	CDD:320109	6/40 (15%)
		TM helix 7	299..325	CDD:320109	5/25 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910