Protein Alignment AdoR and srw-60

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001364794.1
• Gene: srw-60 / 188409
• WormBaseID: WBGene00005807
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 425
• Identity: 70/425 - (16%)
• Similarity: 148/425 - (34%)
• Gaps: 155/425 - (36%)

  Fly    47 FEVLVAIVSIIGNV--LVIIVFRRERKLRRRTNYYI--VSLAMADLLVGALGIPFAILASMGLPR 107
            |:.|.|::.:|.|:  |.||.    ||..|..:.|:  :.:.::|
 Worm    40 FQCLFALIGLIMNMFHLAIIT----RKSMRTNSVYVLMIGITISD-------------------- 80

  Fly   108 NLHACLFTVSLLVVLCTISIFCLVAVSV-DRYWAILYPMAYS------RNVRTRTAIFIISMCW- 164
                 :||:.::|.......|..|..|. |.||.:|..:..:      |.|.|..|.|:....|
 Worm    81 -----MFTMFMVVYNNFNDFFKFVFCSFPDPYWKVLLELILAAIQEIVRRVSTWLAFFMALFRWL 140

  Fly   165 -----VAGTI-------------VGFLPLFGWHADVNHNQE------------CLFV-------- 191
                 ::|::             :|.|.|......:.::|:            |.|:
 Worm   141 IIKNTMSGSLGFLSKSSFALKTNIGVLILSTIITSLTYSQKEVKDVGFEVISTCWFLEKNYKIAH 205

  Fly   192 -------EVMDYNYLVFLYFATIITPAL--LMLAFYTHIYRV-IIKQVRQIVTMNPASDLSRRSS 246
                   |.||.| |.|:.....::..:  ::.||:..|..: :::::||     .|......|:
 Worm   206 TYSVGRSEFMDKN-LNFVEEYAFMSDGIPKMIAAFFLPILAIALVRRLRQ-----AAESRKHLSN 264

  Fly   247 AAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYV 311
            :..:|..                       |:.:.::.:.||.:....|:...:.|::|    |:
 Worm   265 SKPLQTD-----------------------KSIRMVTFMTLFSVFAEGPMGIFSFIRSF----YL 302

  Fly   312 HPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQ 376
            .         .|.:.::|.             :|..:|:.::.|::     ..|.| ::.|
 Worm   303 R---------FSSIEASVE-------------SLDKMLINLVIVNV-----IAHCF-ISMQ---- 335

  Fly   377 SMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQL 411
             |.|..|....:|::.:....|.:.:...:..:::
 Worm   336 -MSSQYRDIATQLFLRKVIRRWKKDRVSVVPQAEM 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	42/226 (19%)
		7tm_1	58..334	CDD:278431	55/335 (16%)
srw-60	NP_001364794.1	7TM_GPCR_Srw	40..351	CDD:402097	69/405 (17%)
		TM helix 2	69..94	CDD:410628	5/49 (10%)
		TM helix 3	113..143	CDD:410628	6/29 (21%)
		TM helix 4	157..177	CDD:410628	3/19 (16%)
		TM helix 5	223..247	CDD:410628	3/23 (13%)
		TM helix 6	268..298	CDD:410628	5/52 (10%)
		TM helix 7	311..337	CDD:410628	7/49 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910