Protein Alignment AdoR and srw-112

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_503820.2
• Gene: srw-112 / 187330
• WormBaseID: WBGene00005859
• Length: 375
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 73/390 - (18%)
• Similarity: 139/390 - (35%)
• Gaps: 109/390 - (27%)

  Fly    47 FEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILA---------S 102
            |.:...:|.|  |:..:||..|........|..:.::|:||::.....|...|:.         |
 Worm    41 FYIYYLVVLI--NLFHVIVLTRPSMRTSSINIIMTAVAIADIISAIYNIHLKIVLILTDIYPCYS 103

  Fly   103 MGLPRN---LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPM--AYSRNVRTRTAIFII-- 160
            ..|..|   |..||:.:......|  |.:..::::..|...:..||  .|.:....:||:.:|
 Worm   104 KNLYHNLIILDNCLYCLQDYTRRC--STWLSLSIATIRTLVVRNPMDPKYEKLSNPKTAVIVIFT 166

  Fly   161 --SMCWVAGTIVGFLPLFGWHADVNHNQEC-------------------LFV--EVMDYNYLVFL 202
              |:| :..|::.:     :.|....|:|.                   ||:  |::.||  :|.
 Worm   167 ICSLC-LPTTVLQY-----FKAGFIENEEANACKGNEMVDEYYYRGLSDLFMDNEMLIYN--IFF 223

  Fly   203 YFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRV 267
            |... :|..|:....|......:|.::|:     .|.:..:.||::..|..:.||
 Worm   224 YLEG-VTSKLIPCLLYPIATVFLIIEIRK-----AAINRKKISSSSSSQQDSSGR---------- 272

  Fly   268 LGAARKRDVKATQNLSIIVLFFMICWIPL---YTINCIKAFCPDCYVHPKLTLFCIILSHLNSAV 329
                      .|:.:..:.:.|.|...|:   |.:|.|.........:..|..|..:.|.|.:|.
 Worm   273 ----------TTKLIFYLTVIFYIGEFPMAVFYILNPILQMSIQWGFYTYLVYFEFLFSTLLTAT 327

  Fly   330 NPVLYAYHL-------KDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQP 387
            .    |.|:       ..::...|:::..                  ..||:|:..:|::.|.:|
 Worm   328 T----AIHMPICLLMSSQYKITAKDVIFG------------------GYQHKLRKSESSVISIRP 370

  Fly   388  387
             Worm   371  370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	43/206 (21%)
		7tm_1	58..334	CDD:278431	61/317 (19%)
srw-112	NP_503820.2	7TM_GPCR_Srw	38..353	CDD:370978	67/371 (18%)
		TM helix 2	69..91	CDD:320109	5/21 (24%)
		TM helix 3	115..137	CDD:320109	4/23 (17%)
		TM helix 4	162..178	CDD:320109	4/16 (25%)
		TM helix 5	220..243	CDD:320109	6/25 (24%)
		TM helix 6	271..296	CDD:320109	6/44 (14%)
		TM helix 7	311..339	CDD:320109	7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910