DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and frpr-15

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_001360519.1 Gene:frpr-15 / 187257 WormBaseID:WBGene00010735 Length:444 Species:Caenorhabditis elegans


Alignment Length:411 Identity:88/411 - (21%)
Similarity:143/411 - (34%) Gaps:85/411 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 VAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGI-PFAILASMGLPRNLHACLF 114
            |.:..||.|.:.|.||.::.......|::.::|:.:|||.....| .|::........|......
 Worm    41 VYLFGIISNSINICVFSQKSMRNHTVNWFFLALSFSDLLTLVASIFVFSVPVYAENSHNPEYIDL 105

  Fly   115 TVSLLV-------VLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGF 172
            :|.|:|       :..|:|::..:.|||.||..:.:|....|...:.....:|    ||..:..|
 Worm   106 SVQLIVWFYPLAQIGLTMSVYVTILVSVHRYLGVCHPFLIRRISNSNAVKAVI----VAAIVFAF 166

  Fly   173 L----PLFGWHADVNHNQECLFVE--------------VMDYNY-LVFLYFATIITPALLMLAFY 218
            :    ..|..||     |.|.|..              :|:..| |:|...|..|....|..|..
 Worm   167 VFNASRWFELHA-----QPCSFGTEGQTNSSVVYPTSLMMNRMYTLIFRNAAYTIVMFFLPFAIL 226

  Fly   219 THIYRVIIKQVRQIVTMNPASDLSR--RSSAAV-----------VQVTTPGRGGHTGTMLRVLGA 270
            |::...||..::|...|..|...||  ||.:.|           .....|...|..|..: ::|.
 Worm   227 TYVNLRIIATLKQSYKMRKAMTTSRSKRSDSTVPTDTIVTKIDGYSAVVPVENGEKGNGI-LMGG 290

  Fly   271 ARKRDVK-------ATQNLSIIVLFFMICWIPLYTINCIK----AFCPDCYVHPKLTLFCIILSH 324
            |....||       .|..|..|...|::..:..:..|.|:    .|..|  :...|......|.:
 Worm   291 ANNGSVKNDKKENGVTVMLVAITTEFLLFNLIAFATNIIELSSIRFFAD--LETLLVELSTFLVN 353

  Fly   325 LNSAVNPVLYAYHLKDFRAALKNLLLKMMGVD----------------------IDQQAEAIHRF 367
            :|.|...::|......:|.....|..|.:|.:                      :|.....::|.
 Worm   354 VNGASTIIIYLIFGSKYRNVFIRLFRKNLGHNFCGKSPKRPIGYSQAHFETTQLLDNSRFDLNRS 418

  Fly   368 SVASQHRLQSMDSNMRSTQPR 388
            ..||..|...:..:.||:..|
 Worm   419 KQASVIRKSDLSPSTRSSSSR 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 44/194 (23%)
7tm_1 58..334 CDD:278431 72/326 (22%)
frpr-15NP_001360519.1 7tmA_FMRFamide_R-like 35..374 CDD:320109 77/344 (22%)
TM helix 1 35..58 CDD:320109 7/16 (44%)
TM helix 2 67..89 CDD:320109 6/21 (29%)
TM helix 3 111..133 CDD:320109 4/21 (19%)
TM helix 4 156..172 CDD:320109 4/19 (21%)
TM helix 5 208..231 CDD:320109 6/22 (27%)
TM helix 6 303..328 CDD:320109 4/24 (17%)
TM helix 7 342..367 CDD:320109 5/24 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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