DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and frpr-7

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_510842.2	Gene:	frpr-7 / 185489	WormBaseID:	WBGene00018191	Length:	414	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	62/262 - (23%)
Similarity:	111/262 - (42%)	Gaps:	40/262 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LNIPYTVFEVLVAIVSIIGNVLVIIVF-RRERKLRRRTNYYIVS--------LAMADLLVGALGI 95
            ||..:|.|.|...|:.   |:|.:.:| |:||.......||:|:        ||.|.||.....:
Worm    32 LNGYFTAFFVFTGIIL---NLLSVSIFLRKERAGTPAIQYYLVTLTLWQTALLANAFLLYSFPNL 93

  Fly    96 PFAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPM---AYSRNVRTRTAI 157
            .:..|.|.|....|:..::|.:  ....|.|::.::.:::|||.|:..|:   |..:..|.|..:
Worm    94 WWGHLVSQGTYVYLYPYVYTFA--NTTHTGSVWIVLTLTIDRYLALCQPLKHRAIGKKRRVRRLM 156

  Fly   158 FIISMCWVAGTIVGFLPLFGWHADVNHNQECLF-------VEVMD-------YNYLVFLYFATII 208
            .::|...|..:|..|   |..|..:..:::.|.       .|:.|       |:.::.:.|.|::
Worm   157 IVVSAMAVMFSIPRF---FEVHVILICDEDQLSCVATIDRTELFDNRLYWTIYHVILAMVFVTLL 218

  Fly   209 TPALLMLAFYTHI---YRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGA 270
             |.|::.|....|   .|..|.:.:.:..  |.||:..|..:.........|..|...::.||..
Worm   219 -PCLILFALTLRITIALRSAIAKRKSLCA--PNSDIDTRCKSIKSSRYNSSRKDHKSNIMLVLVI 280

  Fly   271 AR 272
            |:
Worm   281 AK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	45/193 (23%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	56/244 (23%)
frpr-7	NP_510842.2	7tmA_FMRFamide_R-like	32..344	CDD:320109	62/262 (24%)
		TM helix 1	33..57	CDD:320109	8/26 (31%)
		TM helix 2	67..89	CDD:320109	8/21 (38%)
		TM helix 3	109..131	CDD:320109	3/23 (13%)
		TM helix 4	154..170	CDD:320109	3/15 (20%)
		TM helix 5	205..228	CDD:320109	6/23 (26%)
		TM helix 6	270..295	CDD:320109	4/13 (31%)
		TM helix 7	312..337	CDD:320109
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910