DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and F16C3.1

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_492672.1	Gene:	F16C3.1 / 184568	WormBaseID:	WBGene00008885	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	378	Identity:	76/378 - (20%)
Similarity:	145/378 - (38%)	Gaps:	105/378 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRT-NYYIVSLAMADLLVGALGIPFAIL--------ASMGL 105
            :...:.|:||.:.:|:.|....|||.| |.|:.:|:::..        |.:|        ..|||
Worm    29 IFCFIGILGNSMALILIRTNFWLRRLTSNIYLCTLSVSSC--------FFLLTVIISWADTYMGL 85

  Fly   106 PRNLHA-----CLFTVSLLVVLCTISIFCLVAVSVDRYWAILYP--------MAYSRNVRTRTAI 157
            |  |::     |.|...|......|.::.:..:|.||...:..|        ..:|||:   |..
Worm    86 P--LYSESELGCKFFSFLAHFSDFICVWMISLISCDRMIVLYRPRIRKWVCTKKFSRNM---TIG 145

  Fly   158 FIISMCWVAGTIVGFLPLF-------------------GWHADVNHNQECLFVEVMDYNYLVFLY 203
            |::|      ::|.:..||                   |...|||     ||...:|.:|.:|..
Worm   146 FVLS------SVVLYSWLFLLAGLQIYRLKDGTENTFCGLSQDVN-----LFGFQVDQHYFMFTL 199

  Fly   204 FAT---IITPALLML---AFYTHIYR----------VIIKQVRQIVTMNPASDLS------RRSS 246
            ..|   .:.||:|::   :|.|:.||          :.::.||...|......|:      ..::
Worm   200 MDTALCTLLPAILIIIVNSFSTYRYRQCMKIYSSGVLRVRFVRAPTTQQQQQQLNNDTIQFEETT 264

  Fly   247 AAVVQVTTPGRGGH---TGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPD 308
            .....::|.....:   :.|..|..|..|..|::.::.|.|:...|::..:|.|.:..:::....
Worm   265 VKKYLLSTDNTHSNLPTSSTQSRNCGKLRSSDLQLSRTLIIVTSTFVLLNVPSYAMRILQSIISS 329

  Fly   309 C--------YVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMM 353
            .        ||       .:::.:|:.||...:|.:.....:..||...::::
Worm   330 AGPLFNFVYYV-------TLLIYYLHHAVLFYMYIFWSPQMKKQLKPTAMRLL 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	50/214 (23%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	72/349 (21%)
F16C3.1	NP_492672.1	7tm_classA_rhodopsin-like	26..360	CDD:381740	74/361 (20%)
		TM helix 1	26..47	CDD:381740	4/17 (24%)
		TM helix 2	57..79	CDD:381740	5/29 (17%)
		TM helix 3	96..118	CDD:381740	3/21 (14%)
		TM helix 4	146..162	CDD:381740	5/21 (24%)
		TM helix 5	195..218	CDD:381740	5/22 (23%)
		TM helix 6	297..322	CDD:381740	5/24 (21%)
		TM helix 7	335..360	CDD:381740	6/31 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910