Protein Alignment AdoR and trhr-1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_491990.1
• Gene: trhr-1 / 183056
• WormBaseID: WBGene00016265
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 394
• Identity: 91/394 - (23%)
• Similarity: 167/394 - (42%)
• Gaps: 95/394 - (24%)

  Fly    51 VAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLH----- 110
            ::::.::||:|||.|..:.|.::..||.|:||||.:|.|.....:|..::..:| |.:.:
 Worm    42 ISVIGVLGNLLVITVVLKVRGMKTPTNCYLVSLAASDTLFFFASMPHEMMYLLG-PNDHYLFGSL 105

  Fly   111 ACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPL 175
            .|:....|..:....|...::|.:::||:.|..|.........:.|..||...|:      |..|
 Worm   106 GCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKARTMCTVKRATCIICGIWI------FSML 164

  Fly   176 FGWHADVNHNQECLFVEVMDYNYLVFLYFATII-----TPALLMLAFYTHIYRV----------- 224
            :                   ::|.:||  ||:|     |.....|...:|.|::
 Worm   165 Y-------------------HSYWLFL--ATLIKDDIGTSCSFRLERNSHAYKIVFLLDFVLWYV 208

  Fly   225 ------IIKQVRQIVTMNPASDLSRRS------SAAVVQ---VTTPGRGGHTGTMLRVLG---AA 271
                  ||...:..:|::...|..::|      :..:|:   .::...|.::|....:.|   :|
 Worm   209 LPIMCDIIIYAKIGITLSQCGDKIKKSVKPKIPNEVIVEKSKTSSTSMGHYSGRDSHISGKRNSA 273

  Fly   272 RKRDVKATQNLSIIVLFFMICWIPLYTINCIKAF--------CPDCYVHPKLTLFCIILSHLNSA 328
            :.|: :..:.|:|:|..|.:||:|...:....:|        .||.|::...||..|     |.|
 Worm   274 KGRN-QVVKMLAIVVAVFAVCWLPYRGMVVYNSFVSDPKYSWSPDWYINLSKTLVFI-----NCA 332

  Fly   329 VNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVGE 393
            :||:||......||||.::||.|       ::.......::..:|||.:||. |.|.:|:
 Worm   333 INPILYNLMSARFRAAFRSLLSK-------RKNSGFKSTALNQRHRLNTMDI-MSSAEPK----- 384

  Fly   394 YSPI 397
             ||:
 Worm   385 -SPL 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	41/177 (23%)
		7tm_1	58..334	CDD:278431	72/322 (22%)
trhr-1	NP_491990.1	7tmA_TRH-R	33..349	CDD:320126	77/340 (23%)
		TM helix 1	35..59	CDD:320126	6/16 (38%)
		TM helix 2	68..90	CDD:320126	9/21 (43%)
		TM helix 3	108..130	CDD:320126	3/21 (14%)
		TM helix 4	153..169	CDD:320126	5/40 (13%)
		TM helix 5	196..219	CDD:320126	2/22 (9%)
		TM helix 6	277..302	CDD:320126	7/25 (28%)
		TM helix 7	317..342	CDD:320126	11/29 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910