Protein Alignment AdoR and frpr-18

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_504746.1
• Gene: frpr-18 / 179076
• WormBaseID: WBGene00020586
• Length: 432
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 101/546 - (18%)
• Similarity: 191/546 - (34%)
• Gaps: 186/546 - (34%)

  Fly    49 VLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRN----- 108
            :::.:|.|.||.|..|:|.|........|..:.:|:..|..:..|.||..::.::.|..|
 Worm    12 LVIVLVGIFGNSLSFILFSRPHMRSSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLS 76

  Fly   109 -----LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPM---AYSRNVRTRTAIFIISMCWV 165
                 :...::.::|::..|  |::.:|.::::|:.|:..|:   .:....::|.||.:|
 Worm    77 TYMAYILKLIYPINLMMQTC--SVYIMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVI----- 134

  Fly   166 AGTIVGFLPLFGWHADVNHNQECLFVEVMDYNYLV----FLYFATIITPA---LLMLAFYTHIYR 223
              .:..||          :|    ||...:|.::|    .||...:..|.   ...:.:||.:|
 Worm   135 --IVSAFL----------YN----FVRFFEYRFVVTESGALYEKWLRDPGKHRWYYVGYYTILY- 182

  Fly   224 VIIKQVRQIVT--MNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIV 286
                    |||  :.|.|.::..:...:|.:....:      ..::|...::|:...|..|.|:.
 Worm   183 --------IVTHFLVPFSVMAFANGHVIVAMCKLSK------TRQMLTRQQQREQSTTVMLLIVT 233

  Fly   287 LFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLY--------AYHLKDFRA 343
            ..|.||       |.:.                 .|.:::.::.|.|:        ||.|.|
 Worm   234 FVFAIC-------NTLP-----------------FLLNVSESIFPTLFQDESTRGLAYWLND--- 271

  Fly   344 ALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKN 408
             |.|||     |.::.....|..|:.:.::|           |..:::              |||
 Worm   272 -LSNLL-----VVLNSGTTFIIYFTFSEKYR-----------QTLVFI--------------LKN 305

  Fly   409 SQLLPKCGVVSPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPGS---- 469
            .    .|..||. :||.           |.:.|.....:.:.:|.::.....:..:.:..|
 Worm   306 G----CCATVSD-YNNY-----------TAMSRTASMRISSETGGQIQRQGSKMSNSSRSSDVLL 354

  Fly   470 -----QRSSERNSSS---------------TVPPAPPAPAKPSVPSASYDNH------NYSFSQD 508
                 |:.|||.||.               .:|..|....|..:...|...|      ..:||:|
 Worm   355 KPIYMQKRSERFSSEYNERTCKHLAPFEEHKLPKLPSEKRKKKLHKMSAVEHRGMPEITITFSED 419

  Fly   509 EDEDDDDLEFEDVFVPASSVPNPVQP 534
            ..:.:.|              :|.||
 Worm   420 LPDGEPD--------------SPCQP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	38/187 (20%)
		7tm_1	58..334	CDD:278431	55/297 (19%)
frpr-18	NP_504746.1	7tmA_FMRFamide_R-like	6..299	CDD:320109	71/368 (19%)
		TM helix 1	6..32	CDD:320109	7/19 (37%)
		TM helix 2	39..64	CDD:320109	6/24 (25%)
		TM helix 3	83..113	CDD:320109	6/31 (19%)
		TM helix 4	125..145	CDD:320109	8/40 (20%)
		TM helix 5	175..200	CDD:320109	8/33 (24%)
		TM helix 6	220..250	CDD:320109	9/53 (17%)
		TM helix 7	267..292	CDD:320109	10/33 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910