DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and Htr1b

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_034612.1 Gene:Htr1b / 15551 MGIID:96274 Length:386 Species:Mus musculus


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433
7tm_1 58..334 CDD:278431
Htr1bNP_034612.1 7tmA_5-HT1B_1D 42..376 CDD:320455
TM helix 1 47..73 CDD:320455
TM helix 2 80..106 CDD:320455
TM helix 3 118..148 CDD:320455
Agonist binding. /evidence=ECO:0000250 121..130
DRY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 142..144
TM helix 4 160..183 CDD:320455
TM helix 5 201..230 CDD:320455
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 255..278
TM helix 6 303..333 CDD:320455
Agonist binding. /evidence=ECO:0000250 323..327
TM helix 7 344..369 CDD:320455
NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 361..365
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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