Protein Alignment AdoR and Rxfp2

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_011239323.1
• Gene: Rxfp2 / 140498
• MGIID: 2153463
• Length: 740
• Species: Mus musculus
• Alignment Length: 453
• Identity: 100/453 - (22%)
• Similarity: 179/453 - (39%)
• Gaps: 115/453 - (25%)

  Fly     1 MSAFRYFSITDFSFEGPLLPLHAATTSKDAKDSDSPSSEL--NIPYTVFEVLVAIVSIIGNVLVI 63
            :..|||.|..      |.:.:...:|     |..|.|.:|  |....|...::|.::.:||.|||
Mouse   370 LKTFRYCSYV------PHVRICMPST-----DGISSSEDLLANGILRVSVWVIAFITCVGNFLVI 423

  Fly    64 IVFRRERKLRRRTN----YYIVSLAMADLLVG----ALGI----------PFAILASMGLPRNLH 110
            .|    |.|.:..|    ..|..|..||.|:|    ::|:          .:|:|....:|..|.
Mouse   424 AV----RSLIKAENTTHAMSIKILCCADCLMGVYLFSVGVFDIKYRGQYQKYALLWMESVPCRLL 484

  Fly   111 ACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPL 175
            ..|.|:|     ..:|:..|..::::::..|::|.:..|..:.:||:.:.|: ||.|.::..:|.
Mouse   485 GFLATLS-----TEVSVLLLTFLTLEKFLVIVFPFSNLRLGKRQTAVALASI-WVVGFLIAAVPF 543

  Fly   176 -----FGWHADVN------HNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQV 229
                 ||.....|      |..:........|:..:||        .:.:|||..    ::|..|
Mouse   544 TREDYFGNFYGKNGVCFPLHYDQAEDFGSRGYSLGIFL--------GVNLLAFLV----IVISYV 596

  Fly   230 RQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWI 294
            ....:::       :::....:|.:     |.|           ::|........||....||||
Mouse   597 TMFCSIH-------KTALQTAEVRS-----HIG-----------KEVAVANRFFFIVFSDAICWI 638

  Fly   295 PLYTINCIKAFCPDCYVHPKLTLFCII-LSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDID 358
            |::.:..:...  ...:...:|.:.:: ...:|||:||:||......|:..||.||.|
Mouse   639 PVFVVKILSLL--QVEIPGTITSWIVVFFLPVNSALNPILYTLTTSFFKDKLKQLLHK------- 694

  Fly   359 QQAEAIHRFSVASQHRLQSMDSNMRST-QPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVVSP 420
                  ||.....:.:.:|:.:::..| :..|.:|..|.|       ||.:|.:.|    |||
Mouse   695 ------HRRKPIFKVKKKSLSASIVWTDESSLKLGVLSKI-------ALGDSIMKP----VSP 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	46/196 (23%)
		7tm_1	58..334	CDD:278431	64/305 (21%)
Rxfp2	XP_011239323.1	LDLa	31..66	CDD:238060
		LRR	104..353	CDD:227223
		leucine-rich repeat	125..148	CDD:275380
		LRR_8	148..207	CDD:338972
		leucine-rich repeat	149..172	CDD:275380
		leucine-rich repeat	173..196	CDD:275380
		leucine-rich repeat	197..220	CDD:275380
		leucine-rich repeat	221..244	CDD:275380
		leucine-rich repeat	245..268	CDD:275380
		leucine-rich repeat	269..292	CDD:275380
		leucine-rich repeat	293..316	CDD:275380
		leucine-rich repeat	317..340	CDD:275380
		leucine-rich repeat	341..360	CDD:275380
		7tm_GPCRs	403..688	CDD:391938	69/331 (21%)
		TM helix 1	403..429	CDD:341315	9/29 (31%)
		TM helix 2	436..461	CDD:341315	7/24 (29%)
		TM helix 3	481..511	CDD:341315	6/34 (18%)
		TM helix 4	522..544	CDD:341315	7/22 (32%)
		TM helix 5	572..601	CDD:341315	8/40 (20%)
		TM helix 6	617..647	CDD:341315	9/40 (23%)
		TM helix 7	656..681	CDD:341315	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910