| Sequence 1: | NP_651772.1 | Gene: | AdoR / 43583 | FlyBaseID: | FBgn0039747 | Length: | 774 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000667.1 | Gene: | ADORA2B / 136 | HGNCID: | 264 | Length: | 332 | Species: | Homo sapiens |
| Alignment Length: | 369 | Identity: | 114/369 - (30%) |
|---|---|---|---|
| Similarity: | 178/369 - (48%) | Gaps: | 67/369 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 44 YTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRN 108
Fly 109 LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFL 173
Fly 174 PLFGWHA------------DVNHNQ-----ECLFVEVMDYNYLV-FLYFATIITPALLMLAFYTH 220
Fly 221 IYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSII 285
Fly 286 VLFFMICWIPLYTINCIKAFCP-DCYVHPKLTL-FCIILSHLNSAVNPVLYAYHLKDFRAALKNL 348
Fly 349 LLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRSTQPRLYVG 392 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| AdoR | NP_651772.1 | 7tm_4 | 52..>220 | CDD:304433 | 69/185 (37%) |
| 7tm_1 | 58..334 | CDD:278431 | 98/295 (33%) | ||
| ADORA2B | NP_000667.1 | 7tmA_Adenosine_R_A2B | 8..301 | CDD:320197 | 108/320 (34%) |
| TM helix 1 | 9..35 | CDD:320197 | 9/24 (38%) | ||
| TM helix 2 | 42..69 | CDD:320197 | 16/26 (62%) | ||
| TM helix 3 | 78..108 | CDD:320197 | 16/29 (55%) | ||
| TM helix 4 | 122..140 | CDD:320197 | 5/17 (29%) | ||
| Agonist binding. /evidence=ECO:0000250 | 173..182 | 2/8 (25%) | |||
| TM helix 5 | 179..209 | CDD:320197 | 10/29 (34%) | ||
| TM helix 6 | 227..257 | CDD:320197 | 11/29 (38%) | ||
| Agonist binding. /evidence=ECO:0000250 | 247..254 | 2/6 (33%) | |||
| Agonist binding. /evidence=ECO:0000250 | 266..276 | 2/9 (22%) | |||
| TM helix 7 | 269..294 | CDD:320197 | 13/24 (54%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165150900 | |
| Domainoid | 1 | 1.000 | 181 | 1.000 | Domainoid score | I3483 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BF5B | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000536 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40873 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24246 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5322 |
| SonicParanoid | 1 | 1.000 | - | - | X919 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.830 | |||||