Protein Alignment AdoR and ADORA1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_000665.1
• Gene: ADORA1 / 134
• HGNCID: 262
• Length: 326
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 111/322 - (34%)
• Similarity: 174/322 - (54%)
• Gaps: 43/322 - (13%)

  Fly    36 PS-SELNIPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAI 99
            || |.....|...|||:|:||:.||||||...:..:.||..|..:|||||:||:.||||.||.||
Human     3 PSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAI 67

  Fly   100 LASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCW 164
            |.::|.....|.||.....:::|...||..|:|::||||..:..|:.|...|..|.|...|:.||
Human    68 LINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCW 132

  Fly   165 VAGTIVGFLPLFGWH----------ADVNHNQ---ECLFVEVMDYNYLV-FLYFATIITPALLML 215
            :...:||..|:|||:          |:.:..:   :|.|.:|:...|:| |.:|..::.|.|||:
Human   133 ILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMV 197

  Fly   216 AFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQ 280
            ..|..::.:|.||            |:::.||:            :|...:..|    :::|..:
Human   198 LIYLEVFYLIRKQ------------LNKKVSAS------------SGDPQKYYG----KELKIAK 234

  Fly   281 NLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFR 342
            :|::|:..|.:.|:||:.:|||..|||.|:....||...|.|:|.|||:||::||:.::.||
Human   235 SLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFR 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	68/181 (38%)
		7tm_1	58..334	CDD:278431	97/289 (34%)
ADORA1	NP_000665.1	7tm_4	18..>137	CDD:304433	50/118 (42%)
		7tm_1	26..288	CDD:278431	97/289 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150902
Domainoid	1	1.000	181	1.000	Domainoid score	I3483
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6485
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	1	1.000	-	-		otm40873
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24246
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X919
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.890