DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and GPRNNA17

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_001688615.1	Gene:	GPRNNA17 / 1275825	VectorBaseID:	AGAP005001	Length:	460	Species:	Anopheles gambiae

Alignment Length:	445	Identity:	92/445 - (20%)
Similarity:	178/445 - (40%)	Gaps:	91/445 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LHAATTSKDAKDS----DSPSSELNIPYT--VFEV-----------LVAIVSIIGNVLVIIVFRR 68
            |:|:|......|:    ::....||:..|  |.|:           |:.:|..|||:|.::||..
Mosquito     2 LNASTVQPPLADARVAMEADGGALNLTETEVVMELIGNFLNFYYMPLLVVVGSIGNILSVLVFFN 66

  Fly    69 ERKLRRRTNYYIVSLAMAD--LLVGALGIPFAILASMGLPRNLHACLFTVSLLVVLCTISIFCLV 131
            .:..:..::||:.:|.::|  .|||......:........|..:..|||.: ..|...:|::.:|
Mosquito    67 TKLKKLSSSYYLAALGISDTCYLVGLFVTWLSFFQVHIYTREPYCQLFTYT-SGVSSFLSVWYVV 130

  Fly   132 AVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMD- 195
            |.:.:|:..:.||:........|.|..||:...:.|::.....:|  :|...:::.. .|.:.|
Mosquito   131 AFTFERFIVVRYPLKRQSWCTVRRAKTIIACLTMVGSVHSVPYIF--YAGTQYSERS-NVTICDM 192

  Fly   196 ----------YNY----LVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTM---NPAS-DLS 242
                      :||    :||:...|||. .|..:..:| ::|  ...:|:.:|:   .|:: ::.
Mosquito   193 RKEYTSQMEIFNYIDTVIVFVVPFTIIV-VLNSVTSFT-VWR--FAGLRRNMTLPKRKPSNLEIR 253

  Fly   243 RRSSAAVVQVTTPGRGG-----------------------------HTGTMLRVLGAAR--KRDV 276
            |:.|.........||.|                             :...:.|..|..|  ...:
Mosquito   254 RQLSFQYFSTHPNGRNGILRRSSMSMKDRNFFINITLFALFTLSLRYDRLLYRTAGENRMLHSQM 318

  Fly   277 KATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTL----FCIILSHLNSAVNPVLYAYH 337
            |.|:.|.|:...|:...:|.|.:. ::||...  .|..||:    :|.:....|..:|.:||...
Mosquito   319 KVTKMLLIVSSVFVCLNLPSYVMR-VRAFVET--GHSYLTILVQYYCYLFFITNFGINFILYCIS 380

  Fly   338 LKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNM---RSTQPRL 389
            .::||.|:..:..:.....::|:..:    ...:|..|.....|:   |::.|.|
Mosquito   381 GQNFRKAVIEMFRRHRKSRVNQEPNS----GCGTQSELLRAYGNLALRRTSTPML 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	42/184 (23%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	68/331 (21%)
GPRNNA17	XP_001688615.1	7tm_4	51..>165	CDD:304433	29/114 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910