Protein Alignment AdoR and GPRMAC1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_314486.1
• Gene: GPRMAC1 / 1275250
• VectorBaseID: AGAP010513
• Length: 662
• Species: Anopheles gambiae
• Alignment Length: 643
• Identity: 133/643 - (20%)
• Similarity: 225/643 - (34%)
• Gaps: 204/643 - (31%)

  Fly     6 YFSITDFSFEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEVLVAIVSIIGNVLVIIVFRRER 70
            :|::|..|   ..||....|.....:|..:.|....|...:...:::|:::.|||:|:|.|:.::
Mosquito    38 FFNVTSSS---DSLPTANGTLEVLVEDPPTYSLAQIIILGIIATVLSILTVAGNVMVMISFKIDK 99

  Fly    71 KLRRRTNYYIVSLAMADLLVGALGIP-FAILASMGL-PRNLHACLFTVSLLVVLCTISIFCLVAV 133
            :|:..:||::.|||:||..:|.:.:| |::...:|. |...|.|...::|..:....|:..|:.:
Mosquito   100 QLQTISNYFLFSLAIADFAIGLISMPLFSVTTLLGYWPLGPHICDTWLALDYLASNASVLNLLII 164

  Fly   134 SVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGW-HADVNH---NQECLFVEVM 194
            |.|||:::..|:.|.....|..|..:|...|....::....::.| :.:...   .:|| :::.:
Mosquito   165 SFDRYFSVTRPLTYRAKRTTTRAAIMIGAAWGISLLLWPPWIYSWPYIEGKRTVPEKEC-YIQFI 228

  Fly   195 DYNYLVFLYFATII----TPALLMLAFYTHIYRVIIKQVRQI--VTMNPASDLSRRSSAAVVQVT 253
            :.|:  ::.|.|.|    .|..:|...|..|:|...|:.:::  :|.:...|.|:||:::.....
Mosquito   229 ETNH--YITFGTAIAAFYVPVTVMCFLYYRIWRETKKRQKELKNLTGDRKKDSSKRSNSSDENTA 291

  Fly   254 TPGRGGHTGTMLRVLGAA-------RKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPD-CY 310
            ....|||      ||.|:       |.|...:....|:            |..|   |..|| .|
Mosquito   292 VNHSGGH------VLPASVAEDGWRRPRSESSADAESV------------YMTN---AVLPDGAY 335

  Fly   311 VHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRL 375
            .|..|:                                                         |.
Mosquito   336 GHGMLS---------------------------------------------------------RR 343

  Fly   376 QSMDSNMRSTQPRLYVG---EYSPIWLRQQQEALKNSQLLPKCGVVSPCFNNINQTVAAVASVTT 437
            .|:..|....:|..:.|   |:...|....:|
Mosquito   344 SSITMNGVPKKPTTFFGGIKEWCIAWWHSGRE--------------------------------- 375

  Fly   438 DLEREMWNIVEASSGAELGETSYEF---PSPAPGSQRSSERNSSSTVPPAPPAPAKPSVP----- 494
            |.:...:::.|.|   :||.||...   |..|....||   |..|.:|...|.|.:|::|
Mosquito   376 DSDDYGYDVEEPS---DLGCTSLNVIRDPYVAGSGGRS---NVVSMIPDISPTPIRPALPPLAHL 434

  Fly   495 --------SASYDNHN----YSFSQDE---------------DED-------DDDLEFEDVFVPA 525
                    |.|..|.|    .|.|||.               ||.       .||:.......|.
Mosquito   435 QDMHGARDSRSLPNSNRLGSRSVSQDSVYTILIRLPPEGGSGDERAPSIKMIQDDVPMSMTVPPR 499

  Fly   526 SSVPNPVQPGIDPVELRRSLALVMREKLRSDDTDSRPMGNNQDLPIDEQSRERPLSTQ 583
            ..:|:.....|.||..||.         .:..||.|       ||:..:...:|||.|
Mosquito   500 RPLPSRDSDYILPVATRRQ---------STATTDFR-------LPLSAKIISKPLSKQ 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	45/177 (25%)
		7tm_1	58..334	CDD:278431	69/295 (23%)
GPRMAC1	XP_314486.1	7tm_4	82..>207	CDD:304433	35/124 (28%)
		7tm_1	87..>276	CDD:278431	48/191 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910