Protein Alignment AdoR and GPRGHP1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_003436383.1
• Gene: GPRGHP1 / 1273750
• VectorBaseID: AGAP003076
• Length: 636
• Species: Anopheles gambiae
• Alignment Length: 656
• Identity: 133/656 - (20%)
• Similarity: 226/656 - (34%)
• Gaps: 173/656 - (26%)

  Fly    42 IPYTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILAS---M 103
            :|.|:|...:.:..|:||:.:.:|..:.:.:...||||:.:||::|.|:...|:|..:..:   .
Mosquito    90 LPITIFYCFIFVAGIVGNLSICVVIAKNKSMHTATNYYLFNLAVSDFLLLLFGMPQELYGTWNPF 154

  Fly   104 GLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPM-AYSRNVRTRTAIFIISMCWVA- 166
            ..|.|..||:....|.......::..:.:.:|:||.||.:|. :::.:..:|...|:|.:..||
Mosquito   155 AYPFNQIACIIMGLLSETAANATVLTITSFTVERYIAICHPFRSHTMSKLSRAIKFVIVIWLVAF 219

  Fly   167 GTIVGFLPLFGWHADVNHNQECLFV-EVMDYNYLV--FLYFATIITPALLMLAFYTHIYRVIIKQ 228
            |........|| ..:.|..:.|... |...:.:.|  ||:|   :.|..|:...|..|...:.|
Mosquito   220 GLATPQALQFG-VVETNTTRLCTIKNEHFSHAFEVSSFLFF---VGPMTLIAVLYVLIGIKLRK- 279

  Fly   229 VRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICW 293
                      |.|.:....|....|||.||          .:|:.|.::.   |..:|..|.|||
Mosquito   280 ----------SKLLQGVKRASSDYTTPPRG----------ISAQSRVIRM---LVAVVATFFICW 321

  Fly   294 IPLYTINCIKAF-----CPDCY---VHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLL 350
            .|.:....:..:     ..:.:   |:..|.....||..|::.:||:||            |::
Mosquito   322 APFHAQRLMAVYGVFSKTENVFFYKVYMVLNYTSGILYFLSTCINPLLY------------NIM- 373

  Fly   351 KMMGVDIDQQAEAIHRFSVASQHRLQ-SMDSNMRST---QPRLY--VGEYSPIWLRQQQEALKNS 409
                         .|:|..||:|.|: |.....||.   |...|  |..|.
Mosquito   374 -------------SHKFRDASRHTLKMSCCGGKRSKSDGQHHTYSAVSRYG-------------- 411

  Fly   410 QLLPKCGVVSPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPG------ 468
              :..||......||       :|.:.|.        :...:|.....:..:...|..|
Mosquito   412 --VTGCGSFKVNSNN-------MACIGTG--------IGLGTGGGNAASKQQHQQPGNGTSATPN 459

  Fly   469 -----SQRSSERNSSSTVPPAPPAPAKPSVPSASYDNHNYSFSQDEDEDDDDLEFEDVFVPASSV 528
                 |..|...|.|......||...:|:...|  |:|..|.|..:               :::.
Mosquito   460 QCQQESNMSLLANESCNRGTMPPIAIRPTFTRA--DSHCISISSSQ---------------STTG 507

  Fly   529 PNPVQPGIDPVELRRSLALVMREKLRSDDTDSRPMGNNQDLPIDEQSRERPLSTQTSPTNGPLPA 593
            .|....|    :|.||                    :|..|.....:.|:|.........|...:
Mosquito   508 TNVSSNG----KLSRS--------------------SNGSLRHGGSALEQPTDHAGGGGGGGRLS 548

  Fly   594 LLRAKLLAGNSNSAHCLPGSTASPAPQEQSGIFVIDSEASPGSNGHKPKYRKGTA--------FT 650
            .:..||..|...........|.:|:..      ::....:..:||.:..|||..:        .:
Mosquito   549 TIAEKLRRGTKKVLAFSKSPTGTPSKS------IVSGACAEVTNGRRKAYRKRNSCDSVDTNTIS 607

  Fly   651 RSSLKK 656
            .||||:
Mosquito   608 NSSLKE 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	43/175 (25%)
		7tm_1	58..334	CDD:278431	68/291 (23%)
GPRGHP1	XP_003436383.1	7tm_4	90..>291	CDD:304433	51/215 (24%)
		7tm_1	106..370	CDD:278431	68/291 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910