Protein Alignment AdoR and GPRNPR1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_003436278.1
• Gene: GPRNPR1 / 1273086
• VectorBaseID: AGAP002881
• Length: 832
• Species: Anopheles gambiae
• Alignment Length: 708
• Identity: 154/708 - (21%)
• Similarity: 261/708 - (36%)
• Gaps: 187/708 - (26%)

  Fly    14 FEGPLLPLHAATTSKDAKDSDSPSSEL-NIP------YTVFEVLVAIVSIIGNVLVIIVFRRERK 71
            |:|.:....||.....|....:.|||: .||      ..||.:::..:.:||||:|.||..:.:.
Mosquito   200 FDGGVAFAAAAAADGTASAGFNDSSEMPQIPEYIRATSMVFCIIIMCLGVIGNVMVPIVILKTKD 264

  Fly    72 LRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNL-----HACLFTVSLL-VVLCTISIFCL 130
            :|..||.::.:|::|||||..:..| .:|..:..|..:     ..|...|..: :.:...|:..:
Mosquito   265 MRNSTNIFLTNLSIADLLVLLVCTP-TVLVEVNSPPEVWVLGEEMCNRAVPFVELTVAHASVLTI 328

  Fly   131 VAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMD 195
            :|:|.:||:||..|:. :..|.|:|...:|  |..|.|:...|..| |.|.       .||.
Mosquito   329 LAISFERYYAICEPLK-AGYVCTKTRALLI--CLAAWTVAAILTSF-WPAS-------FFVG--- 379

  Fly   196 YNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGH 260
               .:.|:|   |.|.|:::.    :|.||.|.:.:    ||...:|..||            |:
Mosquito   380 ---SIVLFF---IVPLLILVV----LYSVIAKNLME----NPTIIMSSASS------------GN 418

  Fly   261 TGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPD----------CYVHPKL 315
            .|.:.:.    ||:.:..   |..:|:.|.:|.:|...:.......|.          .|:   |
Mosquito   419 RGNVYKY----RKQVIFM---LGAVVVSFFVCLLPFRALTLWIIIVPSEAIVSIGIERFYI---L 473

  Fly   316 TLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAI------------HRFS 368
            ..||.|:.::|||:||:||......||    |..|:::|.....::::|            |..|
Mosquito   474 LYFCRIMLYMNSAINPILYNLMSSKFR----NGFLQLLGCGKIVRSDSISSGGTRKGGGTFHTGS 534

  Fly   369 --VASQH---------RLQSMDSNMRSTQPRLYVG-EYSPI---WLRQQQEALKNSQLLPKCGVV 418
              ::|.|         |.:|..|...|:..|..|. ::.|:   |...|....::|.::...|..
Mosquito   535 TNLSSSHGTSQRKGGQREESSSSTSSSSLRRPTVQFQHPPVSDEWHPGQGVLRRHSSIISIRGAT 599

  Fly   419 SPCFNNINQTVAAVASVTTDLEREMWNIVEASSGAELGETSYEFPSPAPGSQRSSERNSSSTVPP 483
            .|......::..:.|.....:......|||....|..|               ..::..::..||
Mosquito   600 VPAVAGNGKSHDSAAQPPLSVRANGNKIVEEEEVAGDG---------------CLQQALAAVEPP 649

  Fly   484 APPAPAKPSVPSA-----------------SY----DNHNY---------------------SFS 506
            .|| |..|.:|::                 ||    |.|:|                     :.:
Mosquito   650 TPP-PPPPPLPNSNGFHRFKDRVRIAGSRQSYRARLDFHHYRTGGYVGHGQLTATTTTTTTKNTA 713

  Fly   507 QDEDEDDDDLEFEDVFVPASSVPNPVQPGIDPVELRRSLALVMREKLRSDDTDSR--------PM 563
            ..|:|:..|:         ::.|:...|.......|.||.......|.:..|.:.        ..
Mosquito   714 TTEEEESTDV---------AARPDDEPPRRSNDNNRFSLLHAATAALATATTAATATAVMVIVAA 769

  Fly   564 GNNQDLPIDEQSRERP--LSTQTSPTNGPLPALLRAKLLAGNSNSAHCLPGSTASPAP 619
            ..:.||..:...||||  ......||:.......|     .|...:..|..|..:|:|
Mosquito   770 SGSVDLVDESTDRERPGERFQSVDPTDWTGREAER-----NNGKESPALAASCIAPSP 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	47/173 (27%)
		7tm_1	58..334	CDD:278431	75/291 (26%)
GPRNPR1	XP_003436278.1	7tm_4	242..491	CDD:304433	76/299 (25%)
		7tm_1	251..492	CDD:278431	75/291 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910