Protein Alignment AdoR and GPRNNA3

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_003436282.1
• Gene: GPRNNA3 / 1273080
• VectorBaseID: AGAP002888
• Length: 1230
• Species: Anopheles gambiae
• Alignment Length: 955
• Identity: 197/955 - (20%)
• Similarity: 325/955 - (34%)
• Gaps: 286/955 - (29%)

  Fly    51 VAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLP-RNLHA--- 111
            :.|.:::||.||||...:.||||..|||::|||||||:||....:.|.  ||:.|. |.|..
Mosquito   125 IIIGAVLGNALVIISVHKNRKLRVITNYFVVSLAMADMLVALCAMTFN--ASVELSGRWLFGSFM 187

  Fly   112 CLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLF 176
            |....||.|...|.||..|..:|||||:||:.|:.|...:..||..|:::..||...::.|.|:|
Mosquito   188 CDVWNSLDVYFSTASILHLCCISVDRYFAIVRPLEYPLYMTQRTVFFMLANVWVLPALISFTPIF 252

  Fly   177 -GWHADVNH------NQE-CLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIV 233
             ||:....|      |.: |:|  |::.:|.:.....:...|.::|:..|..||:..::|.:.
Mosquito   253 LGWYTTAEHLAALKINPDLCIF--VVNKSYAIISSSISFWIPGIVMVTMYYRIYKEAVRQRKA-- 313

  Fly   234 TMNPASDLSRRSSAAV---VQVTTPGRG---------------GHTGTMLRVLGAARKRDVKATQ 280
                   |||.||..:   ||:......               .|....||........|:|..|
Mosquito   314 -------LSRTSSNILLNSVQINNASNTLHANHHHHNHHHQHLHHRNHHLRASDCDLGIDIKDIQ 371

  Fly   281 NLSIIVLFFMICWIPLYTINCIKAFCPDCYVHP-----KLTLFCIILSHLN-------------S 327
            :.:...|..:...:|:  :..:.|...|.::.|     :|:...|.|..|.             |
Mosquito   372 HDTHSELSDLDLQVPI--VPTVVANTDDDFLVPSSPPRRLSRSSIDLRDLEYKGEGKIKASDSVS 434

  Fly   328 AVNPVLY----------AYHLKDF----------------RAALK---------------NLLLK 351
            ::.|:.|          ..|:|:.                ||:.|               |.|||
Mosquito   435 SIFPLHYENNLRYSGSEPIHIKEAQQQQQQQQQPNDQQQRRASRKDSFRQINFFQPFFSRNSLLK 499

  Fly   352 ----------------------MMGVDIDQQAEAI------HRFSVASQHRLQSMDSNMR----- 383
                                  .:|. :...|.||      :..||...::.....||..
Mosquito   500 TYIKGGAGGAGGGGGGGGGGSGTVGA-VTGSASAIAGNQLNNNRSVERNNKNNDNRSNNNILDLI 563

  Fly   384 ----------------STQPRLYVGEYSPIWL----RQQQEALKNSQLLPKC------------- 415
                            :|..|..:......:|    :|:|:..||:..|..|
Mosquito   564 NVASSLNKGGDSEKEMNTHKRHQIAASESDFLTMIEKQRQKLGKNTNSLKNCNKDEKELMYALSD 628

  Fly   416 ---------------GVVSPCFNNINQTVAAVASVTTDLERE-MWNIV---EASSGAELGETSYE 461
                           ||...||.|:         |.:::.|: ::.||   |.:.||  .||...
Mosquito   629 SDFSVGLQKQQQQDEGVARRCFKNL---------VGSEVARDGIFKIVLNGEGNGGA--SETGGA 682

  Fly   462 FPSPAPGSQRSSERNSSSTVPPAPPAPAKPSVPSASYDNHNYSFSQDEDEDDDDLEF---EDVFV 523
            .|: |.|.....:..:.|.:  .......|.:....:| |.::.|:.........|.   |...:
Mosquito   683 SPA-AVGLAGGVDGGTESVI--GSGTMGTPDILIGCFD-HGFTGSRPALNSPTVKELVADEGALI 743

  Fly   524 PASSV---------PNPVQPGIDPVELRRSL-ALVMREKLRSDDTDSRPMGNNQ---DLPIDEQS 575
            .|||:         ..|...|...::|..:: .....:.:||....:.|  :||   .|.:...:
Mosquito   744 KASSLKVTDRGDGTSEPTAEGAKVIDLISTINGPAGEDGVRSVKPPAGP--DNQLSTALNVSLNA 806

  Fly   576 RERPLSTQTS---------------------PTNGPLP------ALLRAKLLAGNS----NSAHC 609
            |..|::.|.|                     ||:.|..      |.....:||.|.    :::|
Mosquito   807 RCSPVNIQLSEASTISLDLVATSPKEKLPKVPTSAPATVTTIDIASEMMMMLADNPDIVIDNSH- 870

  Fly   610 LPGSTASPAPQEQSGIFVIDSEASPGSNGHKPKYRKGTAFTRSSLKKSRSCNCSSIAKGRGVHDE 674
             .|:|.||..:      .:....:|......|::.......|.|...:.:.|..:...|....|:
Mosquito   871 -TGATVSPTSR------TVTPSRAPSIMTPSPQHHPRLGRKRQSSTVTYNINVINFQAGDNPDDD 928

  Fly   675 PSSNL----------------CRDQESSVLPQHPQPANHPTENFFSPLRSVGSFMQHSNLFHFLQ 723
            .|..|                .....|.:.|:...|..|   ......|..|:..::.:     .
Mosquito   929 ASFQLNNRNGNGGGTATAGGRSNSSTSELKPKASAPRCH---LHCDQQRQCGARQRYRH-----G 985

  Fly   724 PHAARPTSSTASSTASTPTPSPPPMGQAQEESVPVGLTTSSPSLL 768
            |...|...:::::....|||:.||...|...:.....|...|:.|
Mosquito   986 PGGGRLLRNSSATAPELPTPTRPPTPTAAAAATSAAATVREPARL 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	65/179 (36%)
		7tm_1	58..334	CDD:278431	91/323 (28%)
GPRNNA3	XP_003436282.1	7tm_4	121..>252	CDD:304433	53/128 (41%)
		7tm_1	132..>319	CDD:278431	70/199 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910