Protein Alignment AdoR and adora3.3

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_001361338.1
• Gene: adora3.3 / 101734629
• XenbaseID: XB-GENE-22169677
• Length: 327
• Species: Xenopus tropicalis
• Alignment Length: 342
• Identity: 111/342 - (32%)
• Similarity: 176/342 - (51%)
• Gaps: 43/342 - (12%)

  Fly    44 YTVFEVLVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRN 108
            |...|.::.|.:::||:|||...|....|:..|.|:|||||:|||.||.|.:|.||:.|:|:..:
 Frog    15 YIGVETVIGISAVLGNILVIWAVRLNPSLQNTTFYFIVSLALADLAVGFLVMPLAIVLSLGMHFH 79

  Fly   109 LHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFL 173
            .|||||...|:::|...||..|:|::||||..|..|..|...:.:|...|.|.:.|:...:||.:
 Frog    80 FHACLFICCLIIILTNASILSLLAIAVDRYLRIKIPTRYRIVITSRRICFSICIVWIISFLVGMV 144

  Fly   174 PLFGWH------ADVNHNQECLFVEVMDYNYLV-FLYFATIITPALLMLAFYTHIYRVIIKQVRQ 231
            |:|||:      .:..|...|.|..||...|:| |..|..:..|.::||..|..|:.:|.||:.|
 Frog   145 PMFGWNNRSSLKEEHQHYLNCTFENVMSMEYMVYFNIFGWVYLPLMIMLILYIEIFYLIKKQLNQ 209

  Fly   232 IVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPL 296
                 ..|:..||                        |....::.|..::|::::|.|.:.|:||
 Frog   210 -----SNSNYLRR------------------------GVFYGKEYKTAKSLALVLLLFALSWLPL 245

  Fly   297 YTINCIKAFCPDC----YVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLL--LKMMGV 355
            ..:||::.:.|:.    ...|.:.|| |:|||.|||:||::||:.:|.|:.|..::|  :.|...
 Frog   246 AILNCVQFYNPNVKKLGLYQPTIFLF-ILLSHANSAMNPIIYAFKIKKFKEAYIHILRTILMQKS 309

  Fly   356 DIDQQAEAIHRFSVASQ 372
            .:...|.|.|.....|:
 Frog   310 VVPDAANAEHTMEEISK 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	67/174 (39%)
		7tm_1	58..334	CDD:278431	97/286 (34%)
adora3.3	NP_001361338.1	7tm_GPCRs	13..297	CDD:391938	104/311 (33%)
		TM helix 1	14..40	CDD:341315	9/24 (38%)
		TM helix 2	47..74	CDD:341315	16/26 (62%)
		TM helix 3	83..113	CDD:341315	13/29 (45%)
		TM helix 4	127..145	CDD:341315	5/17 (29%)
		TM helix 5	173..203	CDD:341315	9/29 (31%)
		TM helix 6	222..252	CDD:341315	9/29 (31%)
		TM helix 7	265..290	CDD:341315	14/25 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000536
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000