DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and LOC100494352

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_031757720.1	Gene:	LOC100494352 / 100494352	-ID:	-	Length:	322	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	73/351 - (20%)
Similarity:	126/351 - (35%)	Gaps:	105/351 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 IVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPR---------- 107
            :|..:||.:|:..:....|.....:.|:.:|.::|         ||.|.:  ||.
Frog    32 VVGFLGNCVVLFGYIFCLKNWSSGSVYLFNLCISD---------FAFLCT--LPMLVFSYIHEEW 85

  Fly   108 ------------NLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFII 160
                        .||..|:|          ||..|..:|:|||..|.||.......|..|||.|.
Frog    86 TFGDFLCKCNRYLLHENLYT----------SILFLAFISIDRYMLIKYPFREHILQRKSTAIMIS 140

  Fly   161 SMCWVAGTIVGFLPLFGW--HADVNHNQECL-FVEVMDYNY-LVFLYFATI---ITPALLMLAFY 218
            ...|:..:: ..||:...  ..:||:...|| |....:.:: ||:....|:   :.|..::..||
Frog   141 LGIWILVSL-KILPILFLVKQVEVNNVTICLDFASSGEASWSLVYSLCLTLTGFVIPLCVIWIFY 204

  Fly   219 THIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLS 283
            ..:...:..:.:::..                                  ||:.::.|      :
Frog   205 LKMMCFLKNRNKELTN----------------------------------GASFEKPV------T 229

  Fly   284 IIVL---FFMICWIPLYTINCIK-AFCPDCYVH---PKLTLFCIILSH----LNSAVNPVLY--- 334
            |:||   .|.| :.|.:.|..:: |...|.: |   |.:.....|::.    |||.:|||.|
Frog   230 IVVLAATMFSIXFTPYHVIRNVRIASRTDSWXHSWTPMIIRSAFIIARPIAFLNSMINPVFYFLM 294

  Fly   335 AYHLKDFRAALKNLLLKMMGVDIDQQ 360
            ..|.::...|....|.|.:...|:.:
Frog   295 GDHFREMLLAKIQSLYKSLKCTINSR 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	46/195 (24%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	66/315 (21%)
LOC100494352	XP_031757720.1	7tmA_SUCNR1_GPR91	21..302	CDD:320500	69/331 (21%)
		TM helix 1	23..47	CDD:320500	4/14 (29%)
		TM helix 2	56..77	CDD:320500	8/31 (26%)
		TM helix 3	93..115	CDD:320500	7/31 (23%)
		TM helix 4	138..154	CDD:320500	3/16 (19%)
		TM helix 5	182..205	CDD:320500	5/22 (23%)
		TM helix 6	228..250	CDD:320500	8/27 (30%)
		TM helix 7	270..295	CDD:320500	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910