DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and XB982628

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_002933014.2	Gene:	XB982628 / 100493271	XenbaseID:	XB-GENE-982629	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	361	Identity:	91/361 - (25%)
Similarity:	159/361 - (44%)	Gaps:	62/361 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FSFEGPLLPLHAATTSKDAKDSDSPSS---------ELNIP-YTVFEVLVAIVSIIGNVLVIIVF 66
            :|:|...|.::  ..:|:..::.:|.:         .|.|| ||    ||.::.|.||.|::.|.
Frog    45 WSYEPENLTIY--MVNKNGSNASAPFTGVQLIQSYKPLFIPCYT----LVVLIGIFGNYLLLYVI 103

  Fly    67 RRERKLRRRTNYYIVSLAMADLLVGALGIPFAILAS---MGLPRNLHACLFTVSLLVVLCTISIF 128
            .|.||:...||::|.:||.:|:|:.|..:||.:..:   .|.......|.|...:..|...:|:|
Frog   104 CRTRKMHNVTNFFIGNLAFSDMLMCATCVPFTLAYAFNPQGWVFGKFMCYFVFLMQPVTVYVSVF 168

  Fly   129 CLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAG-TIVGFLPLFGWHADVNHNQECL--- 189
            .|.|::||||:|.::|:  .:.:...|.|:::...|:.. .:||  |.......|...||..
Frog   169 TLTAIAVDRYYATVHPL--KKRISVTTCIYVLMGIWLLSCALVG--PAIAHTYHVEFQQEGFTIC 229

  Fly   190 --FVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQV 252
              |....:...|.:.|...|||..|.:.|.......:.:|...::|..:|.     :|.|...::
Frog   230 EEFWMGKETERLAYAYSTLIITYILPLSAVSLSYICITVKLKNRVVPGHPT-----QSQAEFDRL 289

  Fly   253 TTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIK-----AFCPDCYVH 312
                               |||  |..:.:.::|..|.|||:|::..|.|:     ......::|
Frog   290 -------------------RKR--KIFRLIVLVVTAFGICWLPIHVFNIIRDIDINLINKHYFLH 333

  Fly   313 PKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNL 348
              :.|||...:..:|..||.|||:....||:.|:.:
Frog   334 --IQLFCHWFAMSSSCCNPFLYAWLHDRFRSELRKM 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	49/176 (28%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	72/289 (25%)
XB982628	XP_002933014.2	7tmA_PrRP_R	79..364	CDD:320516	85/320 (27%)
		TM helix 1	80..106	CDD:320516	12/29 (41%)
		TM helix 2	113..138	CDD:320516	10/24 (42%)
		TM helix 3	152..182	CDD:320516	12/29 (41%)
		TM helix 4	193..214	CDD:320516	6/22 (27%)
		TM helix 5	240..269	CDD:320516	7/28 (25%)
		TM helix 6	289..319	CDD:320516	11/50 (22%)
		TM helix 7	332..357	CDD:320516	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910