DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and LOC100491706

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_002944439.2	Gene:	LOC100491706 / 100491706	-ID:	-	Length:	885	Species:	Xenopus tropicalis

Alignment Length:	137	Identity:	33/137 - (24%)
Similarity:	46/137 - (33%)	Gaps:	38/137 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 KLTLFCIILSHLNSAVNPVLYAYHLKDFRAAL---KNLLLKMMGVDIDQQAEAIHRFSVASQHRL 375
            |.:|..:|||.         |.|...|.....   ||||....|:|     |:.::....|.|..
Frog   288 KTSLAQMILSE---------YPYLRGDLEQIFLNPKNLLFIFDGLD-----ESKNQVDFKSSHLC 338

  Fly   376 QSMDSNMRSTQPRLYVGEYSPIWLRQQQEALKNSQLLPKCGVVSPCFNNINQTVAAVASVTTDLE 440
            ....|:          |:.|.|.:     :|....||..|.|:      |......||.:..|:.
Frog   339 NDPQSS----------GDSSIIVV-----SLVKQTLLEGCSVL------ITSRPTRVAEIDVDIF 382

  Fly   441 REMWNIV 447
            ..|..||
Frog   383 HRMSQIV 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	5/19 (26%)
LOC100491706	XP_002944439.2	P-loop_NTPase	241..406	CDD:393355	33/137 (24%)
		NLRC4_HD2	541..651	CDD:375325
		LRR_RI	<653..801	CDD:393385
		leucine-rich repeat	687..710	CDD:275380
		leucine-rich repeat	711..735	CDD:275380
		leucine-rich repeat	740..767	CDD:275380
		LRR_RI	748..>865	CDD:393385
		leucine-rich repeat	768..789	CDD:275380
		leucine-rich repeat	790..824	CDD:275380
		leucine-rich repeat	853..876	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165169843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930